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Physical activity, sleep, and wound healing in adults with venous leg ulcers: a prospective observational cohort pilot study protocol


Team and Qiu, Y and McGinnes, RA and Osadnik, C and O'Brien, J and Turnour, L and Bouguettaya, A and Weller, C, Physical activity, sleep, and wound healing in adults with venous leg ulcers: a prospective observational cohort pilot study protocol, OSFPREPRINTS (2020) [Professional, Non Refereed Article]

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DOI: doi:10.31219/



Venous leg ulcers (VLUs) are a common and costly problem. Due to a cycle of healing and recurrence, they are challenging to treat. Adults with VLUs are less likely to be physically active and show greater sleep disturbances than the general population; limited evidence suggests these issues contribute to VLU healing delays. Furthermore, there is limited evidence suggesting that physical activity aids healing outcomes, despite a sound theoretical rationale.


The primary objective is to determine if physical activity and sleep are associated with VLU healing (at 12 weeks). The secondary objectives are to 1) examine the feasibility and acceptability of wActiSleep-BT device wear, and to determine whether physical activity and sleep levels are associated with: 2) delayed healing 3) and recurrence within 24 weeks; 4) adherence to compression therapy; 5) self-reported quality of life; 6) self-reported venous leg ulcer pain; 7) self-reported physical activity.

Design and method

This prospective observational cohort pilot study aims to recruit a convenience sample of 30 adults with VLUs from three hospital-based outpatient wound clinics in Melbourne, Australia. Physical activity and sleep levels will be measured using the wActiSleep-BT device (ActiGraph). VLU healing and recurrence data will be collected from the patientsí medical record. Patientsí self-reported outcomes will be collected using questionnaires.


Findings will provide insight into the relationship between physical activity and sleep with healing, recurrence, compression use, quality of life, pain, and self-reported physical activity levels. It will also determine the feasibility and acceptability of the wActiSleep-BT device in a VLU population.

Item Details

Item Type:Professional, Non Refereed Article
Keywords:physical activity, sleep, venous leg ulcer, wound healing
Research Division:Health Sciences
Research Group:Public health
Research Field:Preventative health care
Objective Division:Health
Objective Group:Public health (excl. specific population health)
Objective Field:Behaviour and health
UTAS Author:O'Brien, J (Dr Jane O'Brien)
ID Code:142044
Year Published:2020
Deposited By:Nursing
Deposited On:2020-12-10
Last Modified:2021-04-01

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