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A new phylogenetic protocol: dealing with model misspecification and confirmation bias in molecular phylogenetics
Citation
Jermiin, LS and Catullo, RA and Holland, BR, A new phylogenetic protocol: dealing with model misspecification and confirmation bias in molecular phylogenetics, NAR Genomics and Bioinformatics, 2, (2) Article lqaa041. ISSN 2631-9268 (2020) [Refereed Article]
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Copyright Statement
Copyright 2020 The Author(s) This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/),
DOI: doi:10.1093/nargab/lqaa041
Abstract
Molecular phylogenetics plays a key role in comparative genomics and has increasingly significant impacts on science, industry, government, public health and society. In this paper, we posit that the current phylogenetic protocol is missing two critical steps, and that their absence allows model misspecification and confirmation bias to unduly influence phylogenetic estimates. Based on the potential offered by well-established but under-used procedures, such as assessment of phylogenetic assumptions and tests of goodness of fit, we introduce a new phylogenetic protocol that will reduce confirmation bias and increase the accuracy of phylogenetic estimates.
Item Details
| Item Type: | Refereed Article |
|---|---|
| Keywords: | molecular phylogenetics, confirmation bias, model misspecification, goodness-of-fit |
| Research Division: | Biological Sciences |
| Research Group: | Evolutionary biology |
| Research Field: | Phylogeny and comparative analysis |
| Objective Division: | Expanding Knowledge |
| Objective Group: | Expanding knowledge |
| Objective Field: | Expanding knowledge in the biological sciences |
| UTAS Author: | Holland, BR (Professor Barbara Holland) |
| ID Code: | 141853 |
| Year Published: | 2020 |
| Deposited By: | Mathematics |
| Deposited On: | 2020-11-26 |
| Last Modified: | 2021-02-16 |
| Downloads: | 1 View Download Statistics |
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