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Genetic structure of native circumpolar populations based on autosomal, mitochondrial, and Y chromosome DNA markers

Citation

Rubicz, R and Melton, PE and Spitsyn, V and Sun, G and Deka, R and Crawford, MH, Genetic structure of native circumpolar populations based on autosomal, mitochondrial, and Y chromosome DNA markers, American Journal of Physical Anthropology, 143, (1) pp. 62-74. ISSN 0002-9483 (2010) [Refereed Article]

Copyright Statement

Copyright 2010 WILEY-LISS, INC.

DOI: doi:10.1002/ajpa.21290

Abstract

This study investigates the genetic structure of the present-day inhabitants of Beringia in order to answer questions concerning their origins and evolution. According to recent studies, the ancestors of Native Americans paused for a time in Beringia, during which they differentiated genetically from other Asians before peopling the New World. Furthermore, the Koryaks of Kamchatka share a "ubiquitous" allele (D9S1120) with Native Americans, indicating they may have descended from the same ancestral Beringian population that gave rise to the New World founders. Our results show that a genetic barrier exists between Kamchatkans (Koryaks and Even) and Bering Island inhabitants (Aleuts, mixed Aleuts, and Russians), based on Analysis of Molecular Variance (AMOVA) and structure analysis of nine autosomal short tandem repeats (STRs). This is supported by mitochondrial DNA evidence, but not by analysis of Y chromosome markers, as recent non-native male admixture into the region appears to have partially obscured ancient population relationships. Our study indicates that while Aleuts are descended from the original New World founders, the Koryaks are unlikely to represent a Beringian remnant of the ancestral population that gave rise to Native Americans. They are instead, like the Even, more recent arrivals to Kamchatka from interior Siberia, and the "ubiquitous" allele in Koryaks may result from recent gene flow from Chukotka. Genbank accession numbers for mtDNA sequences: GQ922935-GQ922973.

Item Details

Item Type:Refereed Article
Keywords:Arctic, Aleut, Russia, mtDNA, STRs, Y-chromosome, American Indian
Research Division:Biological Sciences
Research Group:Genetics
Research Field:Anthropological genetics
Objective Division:Expanding Knowledge
Objective Group:Expanding knowledge
Objective Field:Expanding knowledge in the biological sciences
UTAS Author:Melton, PE (Dr Phillip Melton)
ID Code:141475
Year Published:2010
Web of Science® Times Cited:17
Deposited By:Menzies Institute for Medical Research
Deposited On:2020-10-22
Last Modified:2021-06-30
Downloads:0

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