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Genetic Analysis Workshop 18: Methods and strategies for analyzing human sequence and phenotype data in members of extended pedigrees
journal contribution
posted on 2023-05-22, 03:56 authored by Bickeboller, H, Bailey, JN, Beyene, J, Cantor, RM, Cordell, HJ, Culverhouse, RC, Engelman, CD, Fardo, DW, Ghosh, S, Konig, IR, Bermejo, JL, Phillip MeltonPhillip Melton, Santorico, SA, Satten, GA, L Sun, Tintle, NL, Ziegler, A, MacCluer, JW, Almasy, LGenetic Analysis Workshop 18 provided a platform for developing and evaluating statistical methods to analyze whole-genome sequence data from a pedigree-based sample. In this article we present an overview of the data sets and the contributions that analyzed these data. The family data, donated by the Type 2 Diabetes Genetic Exploration by Next-Generation Sequencing in Ethnic Samples Consortium, included sequence-level genotypes based on sequencing and imputation, genome-wide association genotypes from prior genotyping arrays, and phenotypes from longitudinal assessments. The contributions from individual research groups were extensively discussed before, during, and after the workshop in theme-based discussion groups before being submitted for publication.
History
Publication title
BMC ProceedingsVolume
8Issue
Suppl 1Pagination
1-4ISSN
1753-6561Department/School
Menzies Institute for Medical ResearchPublisher
BioMed Central Ltd.Place of publication
United KingdomRepository Status
- Restricted