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Genetic Analysis Workshop 18: Methods and strategies for analyzing human sequence and phenotype data in members of extended pedigrees

Citation

Bickeboller, H and Bailey, JN and Beyene, J and Cantor, RM and Cordell, HJ and Culverhouse, RC and Engelman, CD and Fardo, DW and Ghosh, S and Konig, IR and Bermejo, JL and Melton, PE and Santorico, SA and Satten, GA and Sun, L and Tintle, NL and Ziegler, A and MacCluer, JW and Almasy, L, Genetic Analysis Workshop 18: Methods and strategies for analyzing human sequence and phenotype data in members of extended pedigrees, BMC Proceedings, 8, (Suppl 1) pp. 1-4. ISSN 1753-6561 (2014) [Contribution to Refereed Journal]


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DOI: doi:10.1186/1753-6561-8-S1-S1

Abstract

Genetic Analysis Workshop 18 provided a platform for developing and evaluating statistical methods to analyze whole-genome sequence data from a pedigree-based sample. In this article we present an overview of the data sets and the contributions that analyzed these data. The family data, donated by the Type 2 Diabetes Genetic Exploration by Next-Generation Sequencing in Ethnic Samples Consortium, included sequence-level genotypes based on sequencing and imputation, genome-wide association genotypes from prior genotyping arrays, and phenotypes from longitudinal assessments. The contributions from individual research groups were extensively discussed before, during, and after the workshop in theme-based discussion groups before being submitted for publication.

Item Details

Item Type:Contribution to Refereed Journal
Keywords:whole-genome sequence, biostatistics, family studies, pedigrees, genetic epidemiology
Research Division:Biological Sciences
Research Group:Genetics
Research Field:Gene mapping
Objective Division:Expanding Knowledge
Objective Group:Expanding knowledge
Objective Field:Expanding knowledge in the mathematical sciences
UTAS Author:Melton, PE (Dr Phillip Melton)
ID Code:141454
Year Published:2014
Deposited By:Menzies Institute for Medical Research
Deposited On:2020-10-21
Last Modified:2021-08-12
Downloads:0

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