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Excess pressure as an analogue of blood flow velocity
Citation
Armstrong, MK and Schultz, MG and Hughes, AD and Picone, DS and Black, JA and Dwyer, N and Roberts-Thomson, P and Sharman, JE, Excess pressure as an analogue of blood flow velocity, Journal of Hypertension, 38 pp. 1-7. ISSN 0263-6352 (2020) [Refereed Article]
Copyright Statement
Copyright © 2020 Wolters Kluwer Health, Inc. Unauthorized reproduction of this article is prohibited.
DOI: doi:10.1097/HJH.0000000000002662
Abstract
Methods: Intra-arterial blood pressure was measured sequentially at the brachial and radial arteries via fluid-filled catheter simultaneously with blood flow velocity waveforms recorded via Doppler ultrasound on the contralateral arm (n = 98, aged 61 ± 10 years, 72% men). Excess pressure was derived from intra-arterial blood pressure waveforms using pressure-only reservoir-excess pressure analysis.
Results: Brachial and radial blood flow velocity waveform morphology were closely approximated by excess pressure derived from their respective sites of measurement (median cross-correlation coefficient r = 0.96 and r = 0.95 for brachial and radial comparisons, respectively). In frequency analyses, coherence between blood flow velocity and excess pressure was similar for brachial and radial artery comparisons (brachial and radial median coherence = 0.93 and 0.92, respectively). Brachial and radial blood flow velocity pulse heights were correlated with their respective excess pressure pulse heights (r = 0.53, P < 0.001 and r = 0.43, P < 0.001, respectively).
Conclusion: Excess pressure is an analogue of blood flow velocity, thus affording the opportunity to derive potentially important information related to arterial blood flow using only the blood pressure waveform.
Item Details
Item Type: | Refereed Article |
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Keywords: | hemodynamics, invasive, pulse wave analysis |
Research Division: | Biomedical and Clinical Sciences |
Research Group: | Cardiovascular medicine and haematology |
Research Field: | Cardiology (incl. cardiovascular diseases) |
Objective Division: | Health |
Objective Group: | Clinical health |
Objective Field: | Clinical health not elsewhere classified |
UTAS Author: | Armstrong, MK (Mr Matthew Armstrong) |
UTAS Author: | Schultz, MG (Dr Martin Schultz) |
UTAS Author: | Picone, DS (Mr Dean Picone) |
UTAS Author: | Black, JA (Dr Andrew Black) |
UTAS Author: | Sharman, JE (Professor James Sharman) |
ID Code: | 141301 |
Year Published: | 2020 |
Deposited By: | Menzies Institute for Medical Research |
Deposited On: | 2020-10-13 |
Last Modified: | 2020-11-11 |
Downloads: | 0 |
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