Wu, F and Pahkala, K and Juonala, M and Rovio, SP and Sabin, MA and Ronnemaa, T and Smith, KJ and Jula, A and Lehtimaki, T and Hutri-Kahonen, N and Kahonen, M and Laitinen, T and Viikari, JSA and Raitakari, OT and Magnussen, CG, Childhood and long-term dietary calcium intake and adult cardiovascular risk in a population with high calcium intake, Clinical Nutrition, 40, (4) pp. 1926-1931. ISSN 0261-5614 (2020) [Refereed Article]
Copyright 2020 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism
Methods: A population-based prospective cohort study in Finland (n = 1029, aged 3-18 years at baseline). Dietary calcium intake was assessed in childhood (1980, baseline) and adulthood (mean of available data from 2001, 2007 and 2011). Long-term dietary calcium intake was calculated as the mean between childhood and adulthood. Outcomes were measured in 2001, 2007, and/or 2011, and the latest available data were used for analyses, including high carotid intima-media thickness, hypertension, low high-density lipoprotein cholesterol, high low-density lipoprotein cholesterol and triglycerides, arterial pulse wave velocity (PWV), carotid artery compliance (CAC), Young's elastic modulus (YEM), and stiffness index (SI).
Results: There were no significant non-linear or linear associations between childhood or long-term dietary calcium intake with any adult cardiovascular outcomes, after adjustment for age, sex, and childhood and adulthood confounders (e.g., body mass index, systolic blood pressure, smoking, physical activity, fruit and vegetable consumption).
Conclusions: Childhood or long-term dietary calcium intake that is higher than the recommended level is not associated with increased cardiovascular risk in adulthood.
|Item Type:||Refereed Article|
|Keywords:||cardiovascular risk, cohort, dietary calcium intake, paediatric|
|Research Division:||Biomedical and Clinical Sciences|
|Research Group:||Cardiovascular medicine and haematology|
|Research Field:||Cardiology (incl. cardiovascular diseases)|
|Objective Group:||Public health (excl. specific population health)|
|UTAS Author:||Wu, F (Dr Feitong Wu)|
|UTAS Author:||Smith, KJ (Dr Kylie Smith)|
|UTAS Author:||Magnussen, CG (Associate Professor Costan Magnussen)|
|Deposited By:||Menzies Institute for Medical Research|
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