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A happiness magnet? Reviewing the evidence for repetitive transcranial magnetic stimulation in major depressive disorder

Citation

Pridmore, W and Pridmore, S, A happiness magnet? Reviewing the evidence for repetitive transcranial magnetic stimulation in major depressive disorder, Australasian Psychiatry, 29, (2) pp. 207-213. ISSN 1039-8562 (2020) [Refereed Article]


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Copyright Statement

Copyright 2020 The Royal Australian and New Zealand College of Psychiatrists

DOI: doi:10.1177/1039856220956474

Abstract

Objectives: First, to conduct a historical review of the evidence for repetitive transcranial magnetic stimulation (rTMS) for major depressive disorder and determine a clinical algorithm. Second, to identify opportunities for research.

Methods: Literature searches were conducted of the MEDLINE database, UpToDate and the Australian National University Library SuperSearch from 1 January 2000 to 30 September 2019. The search terms used were ‘transcranial magnetic stimulation’, ‘major depressive disorder’ and ‘depression’.

Results: There were 24 meta-analyses identified, demonstrating a clear clinical effect. Left high-frequency rTMS had the most evidence. Ideal clinical parameters and study design were explored.

Conclusion: Use of rTMS for some patients with depression is justified. Open research questions include the comparative efficacy of right low-frequency and bilateral stimulation, the role of rTMS in medication-naïve patients, and maintenance of effect.

Item Details

Item Type:Refereed Article
Keywords:transcranial magnetic stimulation, brain stimulation, major depressive disorder, mood disorder, meta-analysis
Research Division:Health Sciences
Research Group:Health services and systems
Research Field:Mental health services
Objective Division:Health
Objective Group:Public health (excl. specific population health)
Objective Field:Mental health
UTAS Author:Pridmore, S (Professor Saxby Pridmore)
ID Code:141087
Year Published:2020
Deposited By:Medicine
Deposited On:2020-09-24
Last Modified:2021-08-11
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