Nielsen, S and Picco, L and Campbell, G and Lintzeris, N and Larance, B and Farrell, M and Degenhardt, L and Bruno, R, Development of a Brief Patient-Administered Screening Tool for Prescription Opioid Dependence for Primary Care Settings, Pain Medicine, 21, (2) pp. e79-e88. ISSN 1526-2375 (2020) [Refereed Article]
Copyright 2019 American Academy of Pain Medicine. All rights reserved.
Objective: To develop a short, patient-administered screening tool that will allow for earlier assessment of prescription opioid dependence (often referred to as addiction) in primary care settings.
Design and Setting: Cross-sectional analysis (Nž 1,134) from the two-year time point of the Pain and Opioids IN Treatment (POINT) cohort was used in the scale development. Subjects. Participants who completed two-year interviews in the POINT study, a prospective cohort study that followed people with chronic noncancer pain over a five-year period, and who were prescribed strong opioids for a minimum of six weeks at baseline.
Methods: An advisory committee provided advice on wording and content for screening in primary care settings. Univariate logistic regression identified individual items that were significantly associated with meeting ICD-11 criteria for prescription opioid dependence. Exploratory and confirmatory factor analysis (EFA and CFA) were conducted, and items were reduced to identify a small item set that were discriminative and shared a simple underlying structure.
Results: Sixty-four variables associated with ICD-11 criteria for prescription opioid dependence were initially identified. Four rounds of EFA were performed, resulting in five items remaining. CFA identified two possible four-item combinations, with the final combination chosen based on greater item endorsement and the results of goodness-of-fit indices.
Conclusions: Addressing prescription opioid dependence is an important part of the global public health challenge surrounding rising opioid-related harm. This study addresses an important initial requisite step to develop a brief screening tool. Further studies are required to validate the tool in clinical settings.
|Item Type:||Refereed Article|
|Keywords:||opioid dependence, opioid use disorder, chronic pain, screening|
|Research Group:||Biological psychology|
|Research Field:||Behavioural neuroscience|
|Objective Group:||Public health (excl. specific population health)|
|Objective Field:||Public health (excl. specific population health) not elsewhere classified|
|UTAS Author:||Bruno, R (Associate Professor Raimondo Bruno)|
|Web of Science® Times Cited:||4|
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