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The association between grip strength measured in childhood, young- and mid-adulthood and prediabetes or type 2 diabetes in mid-adulthood
Citation
Fraser, BJ and Blizzard, L and Buscot, M-J and Schmidt, MD and Dwyer, T and Venn, AJ and Magnussen, CG, The association between grip strength measured in childhood, young- and mid-adulthood and prediabetes or type 2 diabetes in mid-adulthood, Sports Medicine, 51, (1) pp. 175-183. ISSN 0112-1642 (2020) [Refereed Article]
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Copyright Statement
Copyright 2020 the authors. Licensed under Creative Commons Attribution 4.0 International (CC BY 4.0) https://creativecommons.org/licenses/by/4.0/
DOI: doi:10.1007/s40279-020-01328-2
Abstract
Methods: Between 1985 and 2019, 263 participants had their grip strength measured using an isometric dynamometer in childhood (9-15 years), young adulthood (28-36 years) and mid-adulthood (38-49 years). In mid-adulthood, a fasting blood sample was collected and tested for glucose and glycated haemoglobin (HbA1c). Participants were categorized as having prediabetes or type 2 diabetes if fasting glucose levels were ≥ 5.6 mmol or if HbA1c levels were ≥ 5.7% (≥ 39 mmol/mol). A Bayesian relevant life course exposure model examined the association between lifelong grip strength and prediabetes or type 2 diabetes.
Results: Grip strength at each time point was equally associated with prediabetes or type 2 diabetes in mid-adulthood (childhood: 37%, young adulthood: 36%, mid-adulthood: 28%). A one standard deviation increase in cumulative grip strength was associated with 34% reduced odds of prediabetes or type 2 diabetes in mid-adulthood (OR 0.66, 95% credible interval 0.40, 0.98).
Conclusions: Greater grip strength across the life course could protect against the development of prediabetes and type 2 diabetes. Strategies aimed at increasing muscular strength in childhood and maintaining behaviours to improve strength into adulthood could improve future cardiometabolic health. The Association Between Grip Strength Measured in Childhood, Young- and Mid-adulthood and Prediabetes or Type 2 Diabetes in Mid-adulthood.
Item Details
Item Type: | Refereed Article |
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Research Division: | Biomedical and Clinical Sciences |
Research Group: | Clinical sciences |
Research Field: | Endocrinology |
Objective Division: | Health |
Objective Group: | Clinical health |
Objective Field: | Clinical health not elsewhere classified |
UTAS Author: | Fraser, BJ (Dr Brooklyn Fraser) |
UTAS Author: | Blizzard, L (Professor Leigh Blizzard) |
UTAS Author: | Buscot, M-J (Dr Marie-Jeanne Buscot) |
UTAS Author: | Dwyer, T (Professor Terry Dwyer) |
UTAS Author: | Venn, AJ (Professor Alison Venn) |
UTAS Author: | Magnussen, CG (Associate Professor Costan Magnussen) |
ID Code: | 140533 |
Year Published: | 2020 |
Web of Science® Times Cited: | 12 |
Deposited By: | Menzies Institute for Medical Research |
Deposited On: | 2020-08-26 |
Last Modified: | 2021-12-08 |
Downloads: | 18 View Download Statistics |
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