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Risk factors and associated outcomes of hospital readmission in COPD: a systematic review


Njoku, CM and Alqahtani, JS and Wimmer, BC and Peterson, GM and Kinsman, L and Hurst, JR and Bereznicki, BJ, Risk factors and associated outcomes of hospital readmission in COPD: a systematic review, Respiratory Medicine, 173 Article 105988. ISSN 0954-6111 (2020) [Refereed Article]

Copyright Statement

2020 Elsevier Ltd.

DOI: doi:10.1016/j.rmed.2020.105988


Background: Chronic obstructive pulmonary disease (COPD) is a leading cause of unplanned readmission. There is need to identify risk factors for, and strategies to prevent readmission in patients with COPD.

Aim: To systematically review and summarise the prevalence, risk factors and outcomes associated with rehospitalisation due to COPD exacerbation.

Method: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were followed. Five databases were searched for relevant studies.

Results: Fifty-seven studies from 30 countries met the inclusion criteria. The prevalence of COPD-related readmission varied from 2.6 to 82.2% at 30 days, 11.844.8% at 3190 days, 17.963.0% at 6 months, and 25.087.0% at 12 months post-discharge. There were differences in the reported factors associated with readmissions, which may reflect variations in the local context, such as the availability of community-based services to care for exacerbations of COPD. Hospitalisation in the previous year prior to index admission was the key predictor of COPD-related readmission. Comorbidities (in particular asthma), living in a deprived area and living in or discharge to a nursing home were also associated with readmission. Relative to those without readmissions, readmitted patients had higher in-hospital mortality rates, shorter long-term survival, poorer quality of life, longer hospital stay, increased recurrence of subsequent readmissions, and accounted for greater healthcare costs.

Conclusions: in the previous year was the principal risk factor for COPD-related readmissions. Variation in the prevalence and the reported factors associated with COPD-related readmission indicate that risk factors cannot be generalised, and interventions should be tailored to the local healthcare environment.

Item Details

Item Type:Refereed Article
Keywords:COPD, readmission, risk factors, consequences
Research Division:Biomedical and Clinical Sciences
Research Group:Cardiovascular medicine and haematology
Research Field:Respiratory diseases
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Njoku, CM (Ms Maria Chidiamara Noku)
UTAS Author:Wimmer, BC (Dr Barbara Wimmer)
UTAS Author:Peterson, GM (Professor Gregory Peterson)
UTAS Author:Bereznicki, BJ (Dr Bonnie Bereznicki)
ID Code:140383
Year Published:2020
Web of Science® Times Cited:21
Deposited By:Pharmacy
Deposited On:2020-08-12
Last Modified:2021-09-15

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