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The impact of transcranial magnetic stimulation (TMS) on irritability occurring with acute major depressive disorder (MDD)
Citation
Pridmore, S and Rybak, M and Morey, R and May, T, The impact of transcranial magnetic stimulation (TMS) on irritability occurring with acute major depressive disorder (MDD), Australasian Psychiatry, 29, (2) pp. 218-221. ISSN 1039-8562 (2020) [Refereed Article]
Copyright Statement
Copyright 2020 The Royal Australian and New Zealand College of Psychiatrists
DOI: doi:10.1177/1039856220946606
Abstract
Objective: To examine the impact (if any) of a course of transcranial magnetic stimulation (TMS) on irritability occurring in association with acute major depressive disorder (MDD).
Method: In a naturalistic study, patients with MDD according to DSM-5 criteria were given 20 daily TMS treatments. A visual analogue scale for irritability (VAS-I) was developed. Objective tools included the six-item Hamilton Depression Rating Scale (HAMDS6) and the Clinical Global Impression - Severity (CGI-S).
Results: Fifty patients received 53 courses. Forty-seven courses achieved remission on both HAMD6 and CGI-S and six courses did not achieve remission with either. Irritability significantly reduced when MDD remission was achieved but was unchanged when remission was not achieved.
Conclusion: TMS reduces irritability occurring in association with MDD when this treatment affects MDD remission, but not when remission is not affected.
Item Details
Item Type: | Refereed Article |
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Keywords: | transcranial magnetic stimulation, major depressive disorder, irritability |
Research Division: | Health Sciences |
Research Group: | Health services and systems |
Research Field: | Mental health services |
Objective Division: | Health |
Objective Group: | Public health (excl. specific population health) |
Objective Field: | Mental health |
UTAS Author: | Pridmore, S (Professor Saxby Pridmore) |
ID Code: | 140370 |
Year Published: | 2020 |
Deposited By: | Medicine |
Deposited On: | 2020-08-11 |
Last Modified: | 2021-09-28 |
Downloads: | 0 |
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