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Beyond just bacteria: Functional biomes in the gut ecosystem including virome, mycobiome, archaeome and helminths


Vemuri, R and Shankar, EM and Chieppa, M and Eri, R and Kavanagh, K, Beyond just bacteria: Functional biomes in the gut ecosystem including virome, mycobiome, archaeome and helminths, Microorganisms, 8, (4) pp. 1-24. ISSN 2076-2607 (2020) [Refereed Article]


Copyright Statement

Copyright 2020 The Authors. Licensed under Creative Commons Attribution 4.0 International (CC BY 4.0)

DOI: doi:10.3390/microorganisms8040483


Gut microbiota refers to a complex network of microbes, which exerts a marked influence on the host’s health. It is composed of bacteria, fungi, viruses, and helminths. Bacteria, or collectively, the bacteriome, comprises a significant proportion of the well-characterized microbiome. However, the other communities referred to as ‘dark matter’ of microbiomes such as viruses (virome), fungi (mycobiome), archaea (archaeome), and helminths have not been completely elucidated. Development of new and improved metagenomics methods has allowed the identification of complete genomes from the genetic material in the human gut, opening new perspectives on the understanding of the gut microbiome composition, their importance, and potential clinical applications. Here, we review the recent evidence on the viruses, fungi, archaea, and helminths found in the mammalian gut, detailing their interactions with the resident bacterial microbiota and the host, to explore the potential impact of the microbiome on host’s health. The role of fecal virome transplantations, pre-, pro-, and syn-biotic interventions in modulating the microbiome and their related concerns are also discussed.

Item Details

Item Type:Refereed Article
Keywords:rchaeome, fecal virome transplants, gut microbiota, helminths, mycobiome, virome
Research Division:Biomedical and Clinical Sciences
Research Group:Clinical sciences
Research Field:Gastroenterology and hepatology
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Eri, R (Associate Professor Raj Eri)
ID Code:140095
Year Published:2020
Web of Science® Times Cited:47
Deposited By:Health Sciences
Deposited On:2020-07-27
Last Modified:2021-12-20
Downloads:17 View Download Statistics

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