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GORK channel: a master switch of plant metabolism?


Adem, GD and Chen, G and Shabala, L and Chen, Z-H and Shabala, S, GORK channel: a master switch of plant metabolism?, Trends in Plant Science, 25, (5) pp. 434-445. ISSN 1360-1385 (2020) [Refereed Article]

Copyright Statement

2019 Elsevier Ltd. All rights reserved.

DOI: doi:10.1016/j.tplants.2019.12.012


Potassium regulates a plethora of metabolic and developmental response in plants, and upon exposure to biotic and abiotic stresses a substantial K+ loss occurs from plant cells. The outward-rectifying potassium efflux GORK channels are central to this stress-induced K+ loss from the cytosol. In the mammalian systems, signaling molecules such as gamma-aminobutyric acid, G-proteins, ATP, inositol, and protein phosphatases were shown to operate as ligands controlling many K+ efflux channels. Here we present the evidence that the same molecules may also regulate GORK channels in plants. This mechanism enables operation of the GORK channels as a master switch of the cell metabolism, thus adjusting intracellular K+ homeostasis to altered environmental conditions, to maximize plant adaptive potential.

Item Details

Item Type:Refereed Article
Keywords:GORK, potassium, ligand gating, regulation, ion channel
Research Division:Biological Sciences
Research Group:Plant biology
Research Field:Plant physiology
Objective Division:Plant Production and Plant Primary Products
Objective Group:Other plant production and plant primary products
Objective Field:Other plant production and plant primary products not elsewhere classified
UTAS Author:Adem, GD (Mr Getnet Adem)
UTAS Author:Shabala, L (Associate Professor Lana Shabala)
UTAS Author:Shabala, S (Professor Sergey Shabala)
ID Code:139475
Year Published:2020
Web of Science® Times Cited:52
Deposited By:Agriculture and Food Systems
Deposited On:2020-06-17
Last Modified:2020-07-09

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