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GORK channel: a master switch of plant metabolism?
Adem, GD and Chen, G and Shabala, L and Chen, Z-H and Shabala, S, GORK channel: a master switch of plant metabolism?, Trends in Plant Science, 25, (5) pp. 434-445. ISSN 1360-1385 (2020) [Refereed Article]
© 2019 Elsevier Ltd. All rights reserved.
Potassium regulates a plethora of metabolic and developmental response in plants, and upon exposure to biotic and abiotic stresses a substantial K+ loss occurs from plant cells. The outward-rectifying potassium efflux GORK channels are central to this stress-induced K+ loss from the cytosol. In the mammalian systems, signaling molecules such as gamma-aminobutyric acid, G-proteins, ATP, inositol, and protein phosphatases were shown to operate as ligands controlling many K+ efflux channels. Here we present the evidence that the same molecules may also regulate GORK channels in plants. This mechanism enables operation of the GORK channels as a master switch of the cell metabolism, thus adjusting intracellular K+ homeostasis to altered environmental conditions, to maximize plant adaptive potential.
|Item Type:||Refereed Article|
|Keywords:||GORK, potassium, ligand gating, regulation, ion channel|
|Research Division:||Biological Sciences|
|Research Group:||Plant biology|
|Research Field:||Plant physiology|
|Objective Division:||Plant Production and Plant Primary Products|
|Objective Group:||Other plant production and plant primary products|
|Objective Field:||Other plant production and plant primary products not elsewhere classified|
|UTAS Author:||Adem, GD (Mr Getnet Adem)|
|UTAS Author:||Shabala, L (Associate Professor Lana Shabala)|
|UTAS Author:||Shabala, S (Professor Sergey Shabala)|
|Web of Science® Times Cited:||52|
|Deposited By:||Agriculture and Food Systems|
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