Balogun, S and Scott, D and Cicuttini, F and Jones, G and Aitken, D, Longitudinal study of the relationship between physical activity and knee pain and functional limitation in community-dwelling older adults, Archives of Gerontology and Geriatrics, 90 Article 104101. ISSN 0167-4943 (2020) [Refereed Article]
© 2020 Elsevier B.V. All rights reserved.
Method: Participants (N = 1064; 51% women; mean age 63 ± 7.4 years) were measured at baseline, 2.5, and 5 years. PA was measured using pedometers. Knee pain and functional limitation were assessed using the WOMAC scale. A two-part hurdle model, with adjustment for confounders, estimated the association of between-person and within-person variability in PA with knee pain/functional limitation (as the outcome). Linear mixed effect regression models described the association of between-person and within-person variability in knee pain and functional limitation with PA (as the outcome).
Results: Between-person effects showed that participants with a higher 5-year average PA had lower average WOMAC scores (β= -1.17, 95% CI: -1.82, -0.51). Within-person effects showed that at time-points when participants had a higher PA level than average, they also had lower WOMAC scores (β= -0.85, 95% CI: -1.36, -0.35). Conversely, both between-person (β= -15.6, 95% CI: -22.5, -8.8) and within-person increase (β= -7.4, 95% CI: -13.5, -1.4) in WOMAC scores were associated with lower PA.
Conclusion: These findings suggest that PA and knee pain/dysfunctional contribute to the development of one another. Pain can lead to changes in inter- and intraindividual PA levels, but the reverse is also possible - changes in PA results in changes in inter- and intraindividual pain/dysfunctional levels.
|Item Type:||Refereed Article|
|Keywords:||physical activity, WOMAC, bidirectional association, knee pain, osteoarthritis|
|Research Division:||Biomedical and Clinical Sciences|
|Research Group:||Clinical sciences|
|Research Field:||Rheumatology and arthritis|
|Objective Group:||Clinical health|
|Objective Field:||Clinical health not elsewhere classified|
|UTAS Author:||Balogun, S (Dr Saliu Balogun)|
|UTAS Author:||Jones, G (Professor Graeme Jones)|
|UTAS Author:||Aitken, D (Associate Professor Dawn Aitken)|
|Deposited By:||Menzies Institute for Medical Research|
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