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Influence of age on upper arm cuff blood pressure measurement


Picone, DS and Schultz, MG and Otahal, P and Black, JA and Bos, WJ and Chen, C-H and Cheng, H-M and Cremer, A and Dwyer, N and Fonseca, R and Hughes, AD and Kim, H-L and Lacy, PS and Laugesen, E and Ohte, N and Omboni, S and Ott, C and Pereira, T and Pucci, G and Roberts-Thomson, P and Rossen, NB and Schmieder, RE and Sueta, D and Takazawa, K and Wang, J and Weber, T and Westerhof, BE and Williams, B and Yamada, H and Yamamoto, E and Sharman, JE, for the Invasive Blood Pressure Consortium, Influence of age on upper arm cuff blood pressure measurement, Hypertension, 75, (3) pp. 844-850. ISSN 0194-911X (2020) [Refereed Article]

Copyright Statement

Copyright 2020 American Heart Association, Inc.

DOI: doi:10.1161/HYPERTENSIONAHA.119.13973


Blood pressure (BP) is a leading global risk factor. Increasing age is related to changes in cardiovascular physiology that could influence cuff BP measurement, but this has never been examined systematically and was the aim of this study. Cuff BP was compared with invasive aortic BP across decades of age (from 40 to 89 years) using individual-level data from 31 studies (1674 patients undergoing coronary angiography) and 22 different cuff BP devices (19 oscillometric, 1 automated auscultation, 2 mercury sphygmomanometry) from the Invasive Blood Pressure Consortium. Subjects were aged 6411 years, and 32% female. Cuff systolic BP overestimated invasive aortic systolic BP in those aged 40 to 49 years, but with each older decade of age, there was a progressive shift toward increasing underestimation of aortic systolic BP (P<0.0001). Conversely, cuff diastolic BP overestimated invasive aortic diastolic BP, and this progressively increased with increasing age (P<0.0001). Thus, there was a progressive increase in cuff pulse pressure underestimation of invasive aortic PP with increasing decades of age (P<0.0001). These age-related trends were observed across all categories of BP control. We conclude that cuff BP as an estimate of aortic BP was substantially influenced by increasing age, thus potentially exposing older people to greater chance for misdiagnosis of the true risk related to BP.

Item Details

Item Type:Refereed Article
Keywords:sphygmomanometer, aging, blood pressure determination, pulse wave analysis
Research Division:Biomedical and Clinical Sciences
Research Group:Cardiovascular medicine and haematology
Research Field:Cardiology (incl. cardiovascular diseases)
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Picone, DS (Dr Dean Picone)
UTAS Author:Schultz, MG (Dr Martin Schultz)
UTAS Author:Otahal, P (Mr Petr Otahal)
UTAS Author:Black, JA (Dr Andrew Black)
UTAS Author:Dwyer, N (Dr Nathan Dwyer)
UTAS Author:Fonseca, R (Mr Ricardo Fonseca Diaz)
UTAS Author:Roberts-Thomson, P (Dr Philip Roberts-Thomson)
UTAS Author:Sharman, JE (Professor James Sharman)
ID Code:139094
Year Published:2020
Web of Science® Times Cited:13
Deposited By:Menzies Institute for Medical Research
Deposited On:2020-05-26
Last Modified:2021-03-17

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