Cao, P and Li, Y and Tang, Y and Ding, C and Hunter, DJ, Pharmacotherapy for knee osteoarthritis: current and emerging therapies, Expert Opinion on Pharmacotherapy, 21, (7) pp. 797-809. ISSN 1465-6566 (2020) [Refereed Article]
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Areas covered: The authors review the current and emerging therapies for knee OA including traditional OA medications (oral and topical NSAIDs, acetaminophen, and opioids) and emerging treatments including disease-modifying OA drugs. The failures of agents that have been through clinical trials are also summarized. Furthermore, the authors provide their expert perspectives on the future of pharmacotherapy for knee osteoarthritis.
Expert opinion: Compared to traditional OA medications, new disease-modifying OA drugs that act by reducing inflammation and increasing cartilage repair show promise to address the unmet need of disease modification. Many of these new drugs, however, are in the preclinical stage. Long-term RCTs are expected to identify the safety and efficacy of novel OA pharmacotherapy medicines.
|Item Type:||Refereed Article|
|Keywords:||osteoarthritis, disease modification, pain, pharmacotherapy|
|Research Division:||Biomedical and Clinical Sciences|
|Research Group:||Clinical sciences|
|Research Field:||Rheumatology and arthritis|
|Objective Group:||Clinical health|
|Objective Field:||Clinical health not elsewhere classified|
|UTAS Author:||Ding, C (Professor Chang-Hai Ding)|
|Web of Science® Times Cited:||33|
|Deposited By:||Menzies Institute for Medical Research|
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