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Resection of a functioning intrapericardial paraganglioma associated with succinate dehydrogenase B mutation

Citation

Siejka, DA and Vittorio, AF and Thakur, S and Burgess, J and Harkikar, A, Resection of a functioning intrapericardial paraganglioma associated with succinate dehydrogenase B mutation, SAGE open medical case reports ISSN 2050-313X (2019) [Contribution to Refereed Journal]

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DOI: doi:10.1177/2050313X19839530

Abstract

Functional paragangliomas are rare neuroendocrine tumours that secrete catecholamines and are infrequently found in the mediastinum. We report a case of a young male with symptoms of catecholamine excess and a personal and family history of the paraganglioma predisposing succinate dehydrogenase subunit B mutation. The lesion had anatomical intrapericardial juxtaposition to important cardiac anatomy and posed the significant challenge of dissection at surgery. The lesion was successfully resected via sternotomy on cardiopulmonary bypass and confirmed histopathologically as paraganglioma. Intrapericardial paraganglioma is rare and treatment is difficult and time critical considering the proximity of cardiac anatomy as well as malignant potential.

Item Details

Item Type:Contribution to Refereed Journal
Keywords:intrapericardial, paraganglioma, succinate dehydrogenase
Research Division:Biomedical and Clinical Sciences
Research Group:Clinical sciences
Research Field:Endocrinology
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Burgess, J (Professor John Burgess)
ID Code:138745
Year Published:2019
Web of Science® Times Cited:1
Deposited By:Medicine
Deposited On:2020-04-27
Last Modified:2020-04-27
Downloads:0

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