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Resection of a functioning intrapericardial paraganglioma associated with succinate dehydrogenase B mutation
Citation
Siejka, DA and Vittorio, AF and Thakur, S and Burgess, J and Harkikar, A, Resection of a functioning intrapericardial paraganglioma associated with succinate dehydrogenase B mutation, SAGE open medical case reports ISSN 2050-313X (2019) [Contribution to Refereed Journal]
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DOI: doi:10.1177/2050313X19839530
Abstract
Functional paragangliomas are rare neuroendocrine tumours that secrete catecholamines and are infrequently found in the mediastinum. We report a case of a young male with symptoms of catecholamine excess and a personal and family history of the paraganglioma predisposing succinate dehydrogenase subunit B mutation. The lesion had anatomical intrapericardial juxtaposition to important cardiac anatomy and posed the significant challenge of dissection at surgery. The lesion was successfully resected via sternotomy on cardiopulmonary bypass and confirmed histopathologically as paraganglioma. Intrapericardial paraganglioma is rare and treatment is difficult and time critical considering the proximity of cardiac anatomy as well as malignant potential.
Item Details
| Item Type: | Contribution to Refereed Journal |
|---|---|
| Keywords: | intrapericardial, paraganglioma, succinate dehydrogenase |
| Research Division: | Biomedical and Clinical Sciences |
| Research Group: | Clinical sciences |
| Research Field: | Endocrinology |
| Objective Division: | Health |
| Objective Group: | Clinical health |
| Objective Field: | Clinical health not elsewhere classified |
| UTAS Author: | Burgess, J (Professor John Burgess) |
| ID Code: | 138745 |
| Year Published: | 2019 |
| Web of Science® Times Cited: | 2 |
| Deposited By: | Medicine |
| Deposited On: | 2020-04-27 |
| Last Modified: | 2020-04-27 |
| Downloads: | 0 |
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