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Paralytic shellfish toxins (PSTs) are a group of over 50 closely related naturally occurring tetrahydropurine toxins with saxitoxin (STX) as one of the most common and potent. Saxitoxin was first isolated and characterised from the butter clam Saxidomus giganteus as the dihydrochloride salt (Schantz et al., 1975). It is traded as a stand-alone reference material, or included in diagnostic test kits, mainly as the dihydrochloride salt or diacetate salt. This is primarily due to the saxitoxin hydrate (free base) form having poor stability. However, the certificate of analysis for various reference materials may state the concentration as either the salt or free base equivalent, and care must be taken to ensure the value is traceable and used correctly in subsequent calculations.

Item Type:	Contribution to Refereed Journal
Keywords:	seafood, toxins, paralytic shellfish toxins, reporting units, regulation, laboratory analysis, research
Research Division:	Chemical Sciences
Research Group:	Medicinal and biomolecular chemistry
Research Field:	Biologically active molecules
Objective Division:	Health
Objective Group:	Public health (excl. specific population health)
Objective Field:	Food safety
UTAS Author:	Turnbull, AR (Dr Alison Turnbull)
UTAS Author:	Hallegraeff, G (Professor Gustaaf Hallegraeff)
ID Code:	137737
Year Published:	2020
Web of Science® Times Cited:	7
Deposited By:	Ecology and Biodiversity
Deposited On:	2020-03-02
Last Modified:	2020-06-16
Downloads:	0