eCite Digital Repository

Possibilities and limitations of the sequential injection chromatography technique for the determination of anticoccidial agents in water, pharmaceutical formulations and feed

Citation

Bjorklund, E and Maya, F and Bak, SA and Hansen, M and Estela, JM and Cerda, V, Possibilities and limitations of the sequential injection chromatography technique for the determination of anticoccidial agents in water, pharmaceutical formulations and feed, Microchemical Journal, 98 pp. 190-199. ISSN 0026-265X (2011) [Refereed Article]

Copyright Statement

2011 Elsevier B.V. All rights reserved.

DOI: doi:10.1016/j.microc.2011.01.007

Abstract

This paper explores the potential of applying reversed-phase sequential injection chromatography (SIC) to determine the anticoccidial agents Lasalocid and Toltrazuril in various matrices including ground water, pharmaceutical formulations and feed. SIC was performed by connecting a 25נ4.6mm monolithic C18 column to a 2m long pathlength capillary flow cell, where the usage of a flow cell lowers the detection limit compared to a conventional short-distance flow cell, providing a simple detection system for these two compounds which are initially poorly UV absorbents.

The proposed set-up provides a high injection throughput of 12h−1, as well as a limit of detection of 0.019 and 0.010mg/L for Toltrazuril and Lasalocid, respectively. The repeatabilities obtained (n=10) were lower than 2% and 4% for Toltrazuril and Lasalocid, respectively.

Item Details

Item Type:Refereed Article
Keywords:flow analysis, chromatography
Research Division:Chemical Sciences
Research Group:Analytical Chemistry
Research Field:Flow Analysis
Objective Division:Expanding Knowledge
Objective Group:Expanding Knowledge
Objective Field:Expanding Knowledge in the Chemical Sciences
UTAS Author:Maya, F (Mr Fernando Maya Alejandro)
ID Code:137327
Year Published:2011
Web of Science® Times Cited:10
Deposited By:Chemistry
Deposited On:2020-02-10
Last Modified:2020-04-29
Downloads:0

Repository Staff Only: item control page