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Maternal exposure to fine particulate matter from a large coal mine fire is associated with gestational diabetes mellitus: a prospective cohort study

Citation

Melody, SM and Ford, JB and Wills, K and Venn, A and Johnston, FH, Maternal exposure to fine particulate matter from a large coal mine fire is associated with gestational diabetes mellitus: a prospective cohort study, Environmental Research Article 108956. ISSN 0013-9351 (2019) [Refereed Article]


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DOI: doi:10.1016/j.envres.2019.108956

Abstract

Background: In 2014, the Hazelwood coal mine fire was an unprecedented event that resulted in a six-week period of poor air quality in the Latrobe Valley in regional Australia. We aimed to determine whether maternal exposure to fine particulate matter in coal mine fire smoke was associated with selected obstetric complications, including gestational diabetes mellitus, hypertensive disorders of pregnancy and abnormal placentation.

Methods: We defined a complete cohort of pregnant women with births >20 weeks in the Latrobe Valley from March 1, 2012-Dec 31, 2015 utilising administrative perinatal data. Average and peak fine particulate matter (PM2.5) was assigned to residential address at delivery using a chemical transport model. Maternal, meteorological and temporal variables were included in final log-binomial regression models.

Results: 3612 singleton pregnancies were included in the analysis; 766 were exposed to the smoke event. Average maternal PM2.5 exposure was 4.4 μg/m3 (SD 7.7; IQR 2.12). Average peak PM2.5 exposure was 44.9 μg/m3 (SD 57.1; IQR 35.0). An interquartile range increase in peak PM2.5 was associated with a 16% increased likelihood of gestational diabetes mellitus (95%CI 1.09, 1.22; <0.0001). Whereas, an interquartile range increase in average PM2.5 was associated with a 7% increased likelihood of gestational diabetes mellitus (95%CI 1.03, 1.10; <0.0001). Second trimester exposure was of critical importance. No association for hypertensive disorders or abnormal placentation was observed.

Conclusion: This is the first study to examine obstetric complications relating to a discrete smoke event. These findings may guide the public health response to future similar events.

Item Details

Item Type:Refereed Article
Keywords:air pollution, pregnancy complications, gestational diabetes, coal mine fire
Research Division:Medical and Health Sciences
Research Group:Public Health and Health Services
Research Field:Environmental and Occupational Health and Safety
Objective Division:Health
Objective Group:Public Health (excl. Specific Population Health)
Objective Field:Environmental Health
UTAS Author:Melody, SM (Dr Shannon Melody)
UTAS Author:Wills, K (Dr Karen Wills)
UTAS Author:Venn, A (Professor Alison Venn)
UTAS Author:Johnston, FH (Associate Professor Fay Johnston)
ID Code:136428
Year Published:2019
Funding Support:National Health and Medical Research Council (APP1150324)
Deposited By:Menzies Institute for Medical Research
Deposited On:2019-12-19
Last Modified:2020-01-07
Downloads:0

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