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Piloting a clinical laboratory method to evaluate the influence of potential modified risk tobacco products on smokers' quit-related motivation, choice, and behavior
Citation
Ozga-Hess, JE and Felicione, NJ and Ferguson, SG and Dino, G and Elswick, D and Whitworth, C and Turiano, N and Blank, MD, Piloting a clinical laboratory method to evaluate the influence of potential modified risk tobacco products on smokers' quit-related motivation, choice, and behavior, Addictive Behaviors, 99 Article 106105. ISSN 0306-4603 (2019) [Refereed Article]
Copyright Statement
© 2019 Published by Elsevier Ltd.
DOI: doi:10.1016/j.addbeh.2019.106105
Abstract
Research methods are needed that can predict whether the availability of potential modified risk tobacco products (MRTPs) may influence smokers' quit-related motivation, choice, and behavior. This pilot study assessed
the primary outcomes of feasibility and adherence to address this need using an electronic cigarette (ECIG) as a
model MRTP. Cigarette smokers were randomly assigned to use only their own brand of cigarettes (OB-only) or a
second-generation ECIG (18 ng/ml nicotine) plus their OB cigarettes (ECIG+OB) ad libitum for four weeks.
Participants logged products using a mobile device, collected used cigarette filters, and provided saliva samples
every day for analysis of cotinine. They returned to the lab once per week to provide a breath sample and accept
or decline a choice to quit all tobacco products (i.e., cigarettes and/or ECIGs). They also returned for a onemonth follow-up visit. Of those participants randomized (n = 60), 56.7% completed the 4-week intervention and
40.0% completed the follow-up visit. The primary reason for withdrawal was poor adherence with mobile device
use. Comparable numbers of participants in each group chose to make a quit attempt, although more OB-only
participants chose to quit during the first two weeks and more ECIG+OB participants during the last two weeks.
With protocol modifications to reduce participation burden, the current method might ultimately be used by
regulators to predict how smokers' quit-related motivation, choice, and behavior are influenced by current and
future MRTPs.
Item Details
| Item Type: | Refereed Article |
|---|---|
| Keywords: | smoking cessation, e-cigs, electronic cigarettes |
| Research Division: | Psychology |
| Research Group: | Clinical and health psychology |
| Research Field: | Health psychology |
| Objective Division: | Health |
| Objective Group: | Public health (excl. specific population health) |
| Objective Field: | Behaviour and health |
| UTAS Author: | Ferguson, SG (Professor Stuart Ferguson) |
| ID Code: | 134998 |
| Year Published: | 2019 |
| Web of Science® Times Cited: | 5 |
| Deposited By: | Medicine |
| Deposited On: | 2019-09-19 |
| Last Modified: | 2020-08-14 |
| Downloads: | 0 |
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