Hill, E and Clifton, P and Goodwill, AM and Dennerstein, L and Campbell, S and Szoeke, C, Dietary patterns and β-amyloid deposition in aging Australian women, Alzheimer's & Dementia, 4 pp. 535-541. ISSN 1552-5260 (2018) [Refereed Article]
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Copyright 2018 The Authors. Published by Elsevier Inc. on behalf of the Alzheimer’s Association. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Methods: Dietary patterns were extrapolated for 115 participants from the Women's Health Aging Project. Aβ deposition was measured via in vivo F-18 florbetaben positron emission tomography scanning.
Results: Participants were, on average, aged 70 years (±2.63 SD), had 13 years of education (±3.57 SD), a BMI of 28 kg/m2 (±5.46 SD), and a daily energy intake of 5161 kJ (±1679.03 SD). Four dietary patterns were identified: high fat, Mediterranean, junk food, and low fat. Adherence to the junk food diet was a significant predictor of Aβ deposition (β = .10, P = .03).
Discussion: This study highlights the potential of diet to influence neurodegenerative disease and as a potential modifiable lifestyle risk factor for Alzheimer's disease.
|Item Type:||Refereed Article|
|Keywords:||Alzheimer's disease, biomarkers, diet, dietary pattern, factor analysis, neuropathology, nutrition, women, β-amyloid protein|
|Research Division:||Biomedical and Clinical Sciences|
|Research Group:||Nutrition and dietetics|
|Research Field:||Nutrition and dietetics not elsewhere classified|
|Objective Group:||Public health (excl. specific population health)|
|UTAS Author:||Hill, E (Dr Edward Hill)|
|Deposited By:||Menzies Institute for Medical Research|
|Downloads:||9 View Download Statistics|
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