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Introduction: Evidence indicates that associations between diet and Alzheimer's disease may occur through biomarker pathways such as amyloid-β (Aβ); however, few studies have investigated dietary/Aβ relationships, and no study has investigated this relationship in women.

Methods: Dietary patterns were extrapolated for 115 participants from the Women's Health Aging Project. Aβ deposition was measured via in vivo F-18 florbetaben positron emission tomography scanning.

Results: Participants were, on average, aged 70 years (±2.63 SD), had 13 years of education (±3.57 SD), a BMI of 28 kg/m² (±5.46 SD), and a daily energy intake of 5161 kJ (±1679.03 SD). Four dietary patterns were identified: high fat, Mediterranean, junk food, and low fat. Adherence to the junk food diet was a significant predictor of Aβ deposition (β = .10, P = .03).

Discussion: This study highlights the potential of diet to influence neurodegenerative disease and as a potential modifiable lifestyle risk factor for Alzheimer's disease.

Item Type:	Refereed Article
Keywords:	Alzheimer's disease, biomarkers, diet, dietary pattern, factor analysis, neuropathology, nutrition, women, β-amyloid protein
Research Division:	Medical and Health Sciences
Research Group:	Nutrition and Dietetics
Research Field:	Nutrition and Dietetics not elsewhere classified
Objective Division:	Health
Objective Group:	Public Health (excl. Specific Population Health)
Objective Field:	Nutrition
UTAS Author:	Hill, E (Mr Edward Hill)
ID Code:	134903
Year Published:	2018
Deposited By:	Menzies Institute for Medical Research
Deposited On:	2019-09-11
Last Modified:	2019-09-11
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