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Adherence to the Mediterranean diet Is not related to beta-amyloid deposition: data from the Women's Healthy Ageing Project
Citation
Hill, E and Szoeke, C and Dennerstein, L and Campbell, S and Clifton, P, Adherence to the Mediterranean diet Is not related to beta-amyloid deposition: data from the Women's Healthy Ageing Project, Journal of Prevention of Alzheimer's Disease, 5, (2) pp. 137-141. ISSN 2274-5807 (2018) [Refereed Article]
DOI: doi:10.14283/jpad.2018.12
Abstract
Objectives: To investigate the association between Mediterranean diet adherence and beta-amyloid deposition in a cohort of healthy older Australian women.
Design: This study was a cross-sectional investigation of participants from the longitudinal, epidemiologically sourced Women's Healthy Ageing Project which is a follow-up of the Melbourne Women's Midlife Health Project.
Setting: Assessments were conducted at the Centre for Medical Research, Royal Melbourne Hospital in Melbourne, Australia. F-18 Florbetaben positron emission tomography scanning was conducted at the Austin Centre for PET in Victoria, Australia.
Participants: One hundred and eleven Women's Healthy Ageing Project participants were included in the study.
Measurements: Mediterranean diet adherence scores for all participants were calculated from the administration of a validated food frequency questionnaire constructed by the Cancer Council of Victoria. Beta-amyloid deposition was measured using positron emission tomography standardised uptake value ratios.
Results: Gamma regression analysis displayed no association between Mediterranean diet adherence and beta-amyloid deposition. This result was consistent across APOE-ε4 +/- cohorts and with the inclusion of covariates such as age, education, body mass index and cognition.
Conclusions: This study found no association between adherence to the Mediterranean diet and beta-amyloid deposition in a cohort of healthy Australian women.
Item Details
Item Type: | Refereed Article |
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Keywords: | Alzheimer’s disease, diet, Mediterranean diet, beta-Amyloid, deposition |
Research Division: | Biomedical and Clinical Sciences |
Research Group: | Nutrition and dietetics |
Research Field: | Nutrition and dietetics not elsewhere classified |
Objective Division: | Health |
Objective Group: | Public health (excl. specific population health) |
Objective Field: | Nutrition |
UTAS Author: | Hill, E (Dr Eddy Roccati) |
ID Code: | 134901 |
Year Published: | 2018 |
Web of Science® Times Cited: | 9 |
Deposited By: | Menzies Institute for Medical Research |
Deposited On: | 2019-09-11 |
Last Modified: | 2022-08-29 |
Downloads: | 0 |
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