Hill, E and Szoeke, C and Dennerstein, L and Campbell, S and Clifton, P, Adherence to the Mediterranean diet Is not related to beta-amyloid deposition: data from the Women's Healthy Ageing Project, Journal of Prevention of Alzheimer's Disease, 5, (2) pp. 137-141. ISSN 2274-5807 (2018) [Refereed Article]
Objectives: To investigate the association between Mediterranean diet adherence and beta-amyloid deposition in a cohort of healthy older Australian women.
Design: This study was a cross-sectional investigation of participants from the longitudinal, epidemiologically sourced Women's Healthy Ageing Project which is a follow-up of the Melbourne Women's Midlife Health Project.
Setting: Assessments were conducted at the Centre for Medical Research, Royal Melbourne Hospital in Melbourne, Australia. F-18 Florbetaben positron emission tomography scanning was conducted at the Austin Centre for PET in Victoria, Australia.
Participants: One hundred and eleven Women's Healthy Ageing Project participants were included in the study.
Measurements: Mediterranean diet adherence scores for all participants were calculated from the administration of a validated food frequency questionnaire constructed by the Cancer Council of Victoria. Beta-amyloid deposition was measured using positron emission tomography standardised uptake value ratios.
Results: Gamma regression analysis displayed no association between Mediterranean diet adherence and beta-amyloid deposition. This result was consistent across APOE-ε4 +/- cohorts and with the inclusion of covariates such as age, education, body mass index and cognition.
Conclusions: This study found no association between adherence to the Mediterranean diet and beta-amyloid deposition in a cohort of healthy Australian women.
|Item Type:||Refereed Article|
|Keywords:||Alzheimer’s disease, diet, Mediterranean diet, beta-Amyloid, deposition|
|Research Division:||Biomedical and Clinical Sciences|
|Research Group:||Nutrition and dietetics|
|Research Field:||Nutrition and dietetics not elsewhere classified|
|Objective Group:||Public health (excl. specific population health)|
|UTAS Author:||Hill, E (Dr Edward Hill)|
|Web of Science® Times Cited:||5|
|Deposited By:||Menzies Institute for Medical Research|
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