eCite Digital Repository

Nickel(IV)-Catalyzed CH Trifluoromethylation of (Hetero)arenes


Meucci, EA and Nguyen, SN and Camasso, NM and Chong, E and Ariafard, A and Canty, AJ and Sanford, MS, Nickel(IV)-Catalyzed C-H Trifluoromethylation of (Hetero)arenes, Journal of the American Chemical Society, 141, (32) pp. 12872−12879. ISSN 0002-7863 (2019) [Refereed Article]

Copyright Statement

2019 American Chemical Society

DOI: doi:10.1021/jacs.9b06383


This Article describes the development of a stable NiIV complex that mediates C(sp2)H trifluoromethylation reactions. This reactivity is first demonstrated stoichiometrically and then successfully translated to a NiIV-catalyzed CH trifluoromethylation of electron-rich arene and heteroarene substrates. Both experimental and computational mechanistic studies support a radical chain pathway involving NiIV, NiIII, and NiII intermediates.

Item Details

Item Type:Refereed Article
Keywords:nickel catalysis, trifluoromethylation
Research Division:Chemical Sciences
Research Group:Inorganic chemistry
Research Field:Transition metal chemistry
Objective Division:Expanding Knowledge
Objective Group:Expanding knowledge
Objective Field:Expanding knowledge in the chemical sciences
UTAS Author:Ariafard, A (Associate Professor Alireza Ariafard)
UTAS Author:Canty, AJ (Professor Allan Canty)
ID Code:134746
Year Published:2019
Web of Science® Times Cited:45
Deposited By:Chemistry
Deposited On:2019-09-02
Last Modified:2022-08-23

Repository Staff Only: item control page