Froelich, JJ and Cheung, N and de Lange, JAB and Monkhorst, J and Carr, MW and DeLeacy, R, Residuals, recurrences and re-treatment after endovascular repair of intracranial aneurysms: a retrospective methodological comparison, Interventional Neuroradiology, 26, (1) pp. 45-54. ISSN 1591-0199 (2020) [Refereed Article]
Copyright The Author(s) 2019
Methods: Medical records, procedural and follow-up imaging studies of all patients who underwent endovascular treatment for intracranial aneurysms between July 2010 and July 2017 were reviewed retrospectively. Residuals, recurrences and re-treatment rates were assessed regarding initial aneurysm rupture status and applied endovascular technique: primary coiling, balloon- and stent-assisted coiling and flow diversion.
Results: Among 233 aneurysms, residual, recurrence and re-treatment rates were 27, 11.2 and 9.4%, respectively. Compared with unruptured aneurysms, similar residual and recurrence (p > .05), but higher re-treatment rates (4.5% vs. 19%; p < .001) were found for ruptured aneurysms. Residual, recurrence and re-treatment rates were: 13.3, 16 and 12% for primary coiling; 12, 12 and 10.7% for balloon-assisted coiling; 14.9, 7.5 and 4.5% for stent-assisted coiling; 91.9, 0 and 5.4% for flow diversion. Stent-assistance and flow-diversion were associated with lower recurrence and re-treatment rates, when compared with primary- and balloon-assisted coiling (p < .05).
Conclusions: Residuals and recurrences after endovascular treatment of intracranial aneurysms are less common than previously reported. Stent assistance and flow diversion seem associated with reduced recurrence- and re-treatment rates, when compared with primary- and balloon-assisted coiling. Restrained use of stents in ruptured aneurysms may be a contributing factor for higher recurrence/retreatment rates compared to unruptured aneurysms.
|Item Type:||Refereed Article|
|Keywords:||endovascular, intracranial aneurysm, recurrence, residual|
|Research Division:||Biomedical and Clinical Sciences|
|Research Field:||Neurology and neuromuscular diseases|
|Objective Group:||Clinical health|
|Objective Field:||Treatment of human diseases and conditions|
|UTAS Author:||Froelich, JJ (Professor Jens Froelich)|
|UTAS Author:||Cheung, N (Dr Nicholas Cheung)|
|Year Published:||2020 (online first 2019)|
|Web of Science® Times Cited:||5|
|Deposited By:||Menzies Institute for Medical Research|
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