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The impact of residential medication management reviews (RMMRs) on medication regimen complexity


Pouranayatihosseinabad, M and Zaidi, TS and Peterson, G and Nishtala, PS and Hannan, P and Castelino, R, The impact of residential medication management reviews (RMMRs) on medication regimen complexity, Postgraduate Medicine, 130, (6) pp. 575-579. ISSN 0032-5481 (2018) [Refereed Article]

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© 2018 Informa UK Limited, trading as Taylor & Francis Group

DOI: doi:10.1080/00325481.2018.1502016


Objectives: The primary objective of this study was to investigate the impact of RMMRs on medication regimen complexity, as assessed by a validated measure.

Methods: Retrospective analysis of RMMRs pertaining to 285 aged care residents aged ≥ 65 years in Sydney, Australia. Medication regimen complexity was measured using the Medication Regimen Complexity Index (MRCI) at baseline, after pharmacists’ recommendations (assuming that all of the pharmacists’ recommendations were accepted by the General Practitioner (GP)), and after the actual uptake of pharmacists’ recommendations by the GP. Differences in the regimen complexity was measured using the Wilcoxon sign rank test.

Results: Pharmacists made 764 recommendations (average 2.7 recommendations per RMMR), of which 569 (74.5%) were accepted by GPs. The median MRCI at baseline in the sample was 25.5 (IQR = 19.0– 32.5). No statistically significant differences were demonstrated in the MRCI scores after pharmacists’ recommendations (p = 0.53) or after GPs’ acceptance of these recommendations (p = 0.07) compared to the baseline.

Conclusion: Our study revealed high acceptance of pharmacists’ recommendations by GPs. This suggests that RMMRs are useful for identifying and resolving drug-related issues among residents of ACFs. However, our study failed to show a significant effect of RMMRs in reducing the medication regimen complexity, as measured by the MRCI. Further studies are needed to establish the association of medication regimen complexity and clinical outcomes in residents of ACFs.

Item Details

Item Type:Refereed Article
Keywords:Medication regimen complexity; aged care; prescribing; medication reviews; pharmacy services
Research Division:Biomedical and Clinical Sciences
Research Group:Pharmacology and pharmaceutical sciences
Research Field:Clinical pharmacology and therapeutics
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Pouranayatihosseinabad, M (Miss Mahsa Pouranayatihosseinabad)
UTAS Author:Zaidi, TS (Dr Tabish Razi Zaidi)
UTAS Author:Peterson, G (Professor Gregory Peterson)
UTAS Author:Castelino, R (Dr Ronald Castelino)
ID Code:134674
Year Published:2018
Web of Science® Times Cited:5
Deposited By:Pharmacy
Deposited On:2019-08-27
Last Modified:2019-09-17

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