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United colours of chromatin? Developmental genome organisation in flies


Delandre, C and Marshall, OJ, United colours of chromatin? Developmental genome organisation in flies, Biochemical Society Transactions, 47, (2) pp. 691-700. ISSN 0300-5127 (2019) [Refereed Article]

Copyright Statement

2019 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society

DOI: doi:10.1042/BST20180605


The organisation of DNA into differing forms of packaging, or chromatin, controls many of the cell fate decisions during development. Although early studies focused on individual forms of chromatin, in the last decade more holistic studies have attempted to determine a complete picture of the different forms of chromatin present within a cell. In the fruit fly, Drosophila melanogaster, the study of chromatin states has been aided by the use of complementary and cell-type-specific techniques that profile the marks that recruit chromatin protein binding or the proteins themselves. Although many questions remain unanswered, a clearer picture of how different chromatin states affect development is now emerging, with more unusual chromatin states such as Black chromatin playing key roles. Here, we discuss recent findings regarding chromatin biology in flies.

Item Details

Item Type:Refereed Article
Keywords:chromatin, epigenetics, development, drosophila, damid
Research Division:Biological Sciences
Research Group:Genetics
Research Field:Epigenetics (incl. genome methylation and epigenomics)
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Delandre, C (Dr Caroline Delandre)
UTAS Author:Marshall, OJ (Dr Owen Marshall)
ID Code:134673
Year Published:2019
Funding Support:National Health and Medical Research Council (1128784)
Deposited By:Menzies Institute for Medical Research
Deposited On:2019-08-27
Last Modified:2020-08-12

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