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The association between muscular power from childhood to adulthood and adult measures of glucose homeostasis


Fraser, BJ and Blizzard, L and Schmidt, MD and Dwyer, T and Venn, AJ and Magnussen, CG, The association between muscular power from childhood to adulthood and adult measures of glucose homeostasis, Scandinavian Journal of Medicine and Science in Sports, 29, (12) pp. 1909-1916. ISSN 0905-7188 (2019) [Refereed Article]

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Copyright Statement

2019 John Wiley & Sons A/S.

DOI: doi:10.1111/sms.13529


This study aimed to assess whether the longitudinal association between childhood muscular fitness and adult measures of glucose homeostasis persist despite changes in muscular fitness across the life course. This prospective longitudinal study included 586 participants who had their muscular power (standing long jump distance), cardiorespiratory fitness (CRF), and waist circumference measured as children (aged 9, 12, 15 years) and again 20 years later as adults. In adulthood, these participants also provided a fasting blood sample which was tested for glucose and insulin. Glucose homeostasis measures including insulin resistance (HOMA2-IR) and beta cell function (HOMA2-β) were estimated. Child and adult muscular power levels were separated into thirds, and tracking groups (persistently low, decreasing, persistently moderate, increasing, and persistently high) were created. Sex-stratified multivariable linear regression models were used to examine the association between muscular power tracking groups and adult measures of glucose homeostasis. Compared with males with persistently high muscular power, males with increasing and persistently low muscular power had higher fasting insulin (increasing: β = 1.12 mU/L, P = .04; persistently low: β = 2.12 mU/L, P = .001) and HOMA2-β (increasing: β = 8.50%, P = .03; persistently low: β = 11.27%, P = .01) independent of CRF and males with persistently low muscular power had greater fasting insulin (β = 1.22 mU/L, P = .02) and HOMA2-IR (β = 0.14, P = .02) independent of waist circumference. Non-significant associations were present for females. For males, maintaining persistently high muscular power between childhood and adulthood could lead to a healthier adult glucose homeostasis profile.

Item Details

Item Type:Refereed Article
Keywords:cohort, epidemiology, muscle fitness, muscle power
Research Division:Health Sciences
Research Group:Epidemiology
Research Field:Epidemiology not elsewhere classified
Objective Division:Health
Objective Group:Public health (excl. specific population health)
Objective Field:Behaviour and health
UTAS Author:Fraser, BJ (Dr Brooklyn Fraser)
UTAS Author:Blizzard, L (Professor Leigh Blizzard)
UTAS Author:Dwyer, T (Professor Terry Dwyer)
UTAS Author:Venn, AJ (Professor Alison Venn)
UTAS Author:Magnussen, CG (Associate Professor Costan Magnussen)
ID Code:134602
Year Published:2019
Web of Science® Times Cited:6
Deposited By:Menzies Institute for Medical Research
Deposited On:2019-08-22
Last Modified:2020-09-07
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