Granfeldt, A and Avis, SR and Nicholson, TC and Holmberg, MJ and Moskowitz, A and Coker, A and Berg, KM and Parr, MJ and Donnino, MW and Soar, J and Nation, K and Andersen, LW and Callaway, CW and Batigger, BW and Paiva, EF and Wang, TL and O'Neil, BJ and Morley, PT and Welsford, M and Drennan, IR and Reynolds, JC and Neumar, RW and Sandroni, C and Deakin, CD and Nolan, JP and Morley, PT, nternational Liaison Committee on Resuscitation Advanced Life Support Task Force Collaborators, Advanced airway management during adult cardiac arrest: A systematic review, Resuscitation, 139 pp. 133-143. ISSN 0300-9572 (2019) [Refereed Article]
Aim: To systematically review the literature on advanced airway management during adult cardiac arrest in order to inform the International Liaison Committee of Resuscitation (ILCOR) consensus on science and treatment recommendations.
Methods: The review was performed according to PRISMA guidelines and registered on PROSPERO (CRD42018115556). We searched Medline, Embase, and Evidence-Based Medicine Reviews for controlled trials and observational studies published before October 30, 2018. The population included adult patients with cardiac arrest. Two investigators reviewed studies for relevance, extracted data, and assessed the risk of bias of individual studies.
Results: We included 78 observational studies and 11 controlled trials. Most of the observational studies and all of the controlled trials only included patients with out-of-hospital cardiac arrest. The risk of bias for individual observational studies was overall assessed as critical or serious, with confounding and selection bias being the primary sources of bias. Three of the controlled trials, all published in 2018, were powered for clinical outcomes with two comparing a supraglottic airway to tracheal intubation and one comparing bag-mask ventilation to tracheal intubation. All three trials had some concerns regarding risk of bias primarily due to lack of blinding and variable adherence to the protocol. Clinical and methodological heterogeneity across studies, for both the observational studies and the controlled trials, precluded any meaningful meta-analyses.
|Item Type:||Refereed Article|
|Keywords:||airway management, cardiac arrest|
|Research Division:||Medical and Health Sciences|
|Research Group:||Cardiorespiratory Medicine and Haematology|
|Research Field:||Cardiology (incl. Cardiovascular Diseases)|
|Objective Group:||Clinical Health (Organs, Diseases and Abnormal Conditions)|
|Objective Field:||Cardiovascular System and Diseases|
|UTAS Author:||Avis, SR (Ms Suzanne Avis)|
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