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Association of hearing impairment with incident depressive symptoms: a community-based prospective study


Lisan, Q and van Sloten, TT and Lemogne, C and Offredo, L and Climie, RE and Boutouyrie, P and Guibout, C and Thomas, F and Danchin, N and Jouven, X and Empana, J-P, Association of hearing impairment with incident depressive symptoms: a community-based prospective study, American Journal of Medicine, 132, (12) pp. 1441-1449. ISSN 0002-9343 (2019) [Refereed Article]

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Copyright Statement

2019 Elsevier Inc. All rights reserved.

DOI: doi:10.1016/j.amjmed.2019.05.039


Objective: The aim was to investigate the potential association between hearing impairment and incident depressive symptoms.

Methods: Using a prospective community-based cohort study in France (the Paris Prospective Study III), participants aged 50-75 years were recruited between 2008 and 2012 and thereafter followed up every 2 years up to 2018. Hearing impairment, measured at study recruitment by audiometry testing, was defined as a pure tone average >25 decibels in the better ear. Incident depressive symptoms, measured using the validated 13-item Questionnaire of Depression 2nd version, was assessed during follow-up. Multivariate generalized estimating equations were used to compute odds ratio (OR) and 95% confidence intervals (CI).

Results: Among 7591 participants free of depressive symptoms at baseline (mean age 59.8 years, 63% of men), 14.3% had hearing impairment. Over 6 years of follow-up, 479 subjects (6.3%) had incident depressive symptoms. The OR for incident depressive symptoms was 1.36 for subjects with baseline hearing impairment (95% CI, 1.06-1.73). A pooled analysis of 4 published prospective studies yielded a multivariable relative risk of baseline hearing impairment for incident depressive symptoms of 1.29 (95% CI, 1.09-1.53).

Conclusions: In this community-based prospective cohort study of participants aged 50 to 75 years, baseline hearing impairment was associated with a 36% increased odds of incident depressive symptoms.

Item Details

Item Type:Refereed Article
Keywords:cohort study, depressive symptoms, hearing impairment, prospective
Research Division:Health Sciences
Research Group:Epidemiology
Research Field:Epidemiology not elsewhere classified
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Climie, RE (Dr Rachel Climie)
ID Code:134057
Year Published:2019
Web of Science® Times Cited:12
Deposited By:Menzies Institute for Medical Research
Deposited On:2019-07-24
Last Modified:2020-04-28
Downloads:27 View Download Statistics

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