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Long-term survival rates of patients undergoing vitrectomy for diabetic retinopathy in an Australian population: a population-based audit

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Liu, E and Estevez, J and Kaidonis, G and Hassall, M and Phillips, R and Raymond, G and Saha, N and Wong, GHC and Gilhotra, J and Burdon, K and Landers, J and Henderson, T and Newland, H and Lake, S and Craig, JE, Long-term survival rates of patients undergoing vitrectomy for diabetic retinopathy in an Australian population: a population-based audit, Clinical and Experimental Ophthalmology, 47, (5) pp. 598-604. ISSN 1442-6404 (2019) [Refereed Article]


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Copyright 2019 Royal Australian and New Zealand College of Ophthalmologists

DOI: doi:10.1111/ceo.13466

Abstract

Importance: Five-year survival rates in patients undergoing vitrectomy for diabetic retinopathy (DR) vary from 68% to 95%. No study has been conducted in an Australian population.

Background: We aimed to determine the survival rates of patients undergoing diabetic vitrectomy in an Australian population.

Design: Retrospective audit, tertiary centre hospitals and private practices.

Participants: All individuals in South Australia and the Northern Territory who underwent their first vitrectomy for diabetic complications between January 1, 2007 and December 31, 2011.

Methods: An audit of all eligible participants has been completed previously. Survival status as of July 6, 2018 and cause of death were obtained using SA/NT DataLink. Kaplan-Meier survival curves and multivariate cox-regressions were used to analyse survival rates and identify risk factors for mortality.

Main Outcome Measures: Five-, seven- and nine-year survival rates.

Results: The 5-, 7- and 9-year survival rates were 84.4%, 77.9% and 74.7%, respectively. The most common cause of death was cardiovascular disease. Associated with increased mortality independent of age were Indigenous ethnicity (HR = 2.04, 95% confidence interval [CI]: 1.17-3.57, P = 0.012), chronic renal failure (HR = 1.76, 95% CI: 1.07-2.89, P = 0.026) and renal failure requiring dialysis (HR = 2.32, 95% CI: 1.25-4.32, P = 0.008).

Conclusions and Relevance: Long-term survival rates after diabetic vitrectomy in Australia are similar to rates reported in other populations. Indigenous ethnicity and chronic renal failure were the most significant factors associated with long-term mortality. This information can guide allocation of future resources to improve the prognosis of these high risk groups.

Item Details

Item Type:Refereed Article
Keywords:Australia, diabetic retinopathy, long-term mortality, vitrectomy
Research Division:Medical and Health Sciences
Research Group:Ophthalmology and Optometry
Research Field:Ophthalmology
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Hearing, Vision, Speech and Their Disorders
UTAS Author:Burdon, K (Professor Kathryn Burdon)
ID Code:133980
Year Published:2019
Web of Science® Times Cited:2
Deposited By:Menzies Institute for Medical Research
Deposited On:2019-07-18
Last Modified:2019-08-05
Downloads:1 View Download Statistics

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