Liu, E and Estevez, J and Kaidonis, G and Hassall, M and Phillips, R and Raymond, G and Saha, N and Wong, GHC and Gilhotra, J and Burdon, K and Landers, J and Henderson, T and Newland, H and Lake, S and Craig, JE, Long-term survival rates of patients undergoing vitrectomy for diabetic retinopathy in an Australian population: a population-based audit, Clinical and Experimental Ophthalmology, 47, (5) pp. 598-604. ISSN 1442-6404 (2019) [Refereed Article]
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Copyright 2019 Royal Australian and New Zealand College of Ophthalmologists
Background: We aimed to determine the survival rates of patients undergoing diabetic vitrectomy in an Australian population.
Design: Retrospective audit, tertiary centre hospitals and private practices.
Participants: All individuals in South Australia and the Northern Territory who underwent their first vitrectomy for diabetic complications between January 1, 2007 and December 31, 2011.
Methods: An audit of all eligible participants has been completed previously. Survival status as of July 6, 2018 and cause of death were obtained using SA/NT DataLink. Kaplan-Meier survival curves and multivariate cox-regressions were used to analyse survival rates and identify risk factors for mortality.
Main Outcome Measures: Five-, seven- and nine-year survival rates.
Results: The 5-, 7- and 9-year survival rates were 84.4%, 77.9% and 74.7%, respectively. The most common cause of death was cardiovascular disease. Associated with increased mortality independent of age were Indigenous ethnicity (HR = 2.04, 95% confidence interval [CI]: 1.17-3.57, P = 0.012), chronic renal failure (HR = 1.76, 95% CI: 1.07-2.89, P = 0.026) and renal failure requiring dialysis (HR = 2.32, 95% CI: 1.25-4.32, P = 0.008).
Conclusions and Relevance: Long-term survival rates after diabetic vitrectomy in Australia are similar to rates reported in other populations. Indigenous ethnicity and chronic renal failure were the most significant factors associated with long-term mortality. This information can guide allocation of future resources to improve the prognosis of these high risk groups.
|Item Type:||Refereed Article|
|Keywords:||Australia, diabetic retinopathy, long-term mortality, vitrectomy|
|Research Division:||Biomedical and Clinical Sciences|
|Research Group:||Ophthalmology and optometry|
|Objective Group:||Clinical health|
|Objective Field:||Clinical health not elsewhere classified|
|UTAS Author:||Burdon, K (Professor Kathryn Burdon)|
|Web of Science® Times Cited:||6|
|Deposited By:||Menzies Institute for Medical Research|
|Downloads:||7 View Download Statistics|
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