Multidimensional gas chromatography (MDGC) is now established as a technique which can help resolve most of the co-elution problems presenting with conventional gas chromatography for highly complex samples. Essential oils (EOs) are often used in the optimisation and development of novel MDGC methods and related technologies, to demonstrate and assess performance. In this review, recent trends and technical developments in the optimisation of MDGC, modulation and system configuration, pertinent and applied to EO analysis, will be critically discussed. Optimisation of MDGC will be discussed with reference to different column configurations, modulation periods and detection. Attention is given to novel modulation systems, development of multiplex MDGC systems and new approaches which combine heart-cut and comprehensive modes within one system. A section of this review will be dedicated to the preparative application of the MDGC and its application in the isolation of less abundant compounds from complex EO matrices.

Item Type:	Refereed Article
Keywords:	multidimensional gas chromatography, essential oils, heart-cut multidimensional gas chromatography, comprehensive multidimensional gas chromatography, enantioselective multidimensional gas chromatography, optimisation, mass spectrometry
Research Division:	Chemical Sciences
Research Group:	Analytical chemistry
Research Field:	Separation science
Objective Division:	Expanding Knowledge
Objective Group:	Expanding knowledge
Objective Field:	Expanding knowledge in the chemical sciences
UTAS Author:	Lebanov, L (Mr Leo Lebanov)
UTAS Author:	Tedone, L (Ms Laura Tedone)
UTAS Author:	Paull, B (Professor Brett Paull)
ID Code:	133161
Year Published:	2019
Web of Science® Times Cited:	12
Deposited By:	Chemistry
Deposited On:	2019-06-14
Last Modified:	2022-08-25
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