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The effect of blueberry interventions on cognitive performance and mood: a systematic review of randomized controlled trials


Travica, N and D'Cunha, NM and Naumovski, N and Kent, K and Mellor, DD and Firth, J and Georgousopoulou, EN and Dean, OM and Loughman, A and Jacka, F and Marx, W, The effect of blueberry interventions on cognitive performance and mood: a systematic review of randomized controlled trials, Brain, Behavior, and Immunity ISSN 0889-1591 (2019) [Refereed Article]

Copyright Statement

2019 Elsevier Inc. All rights reserved.

DOI: doi:10.1016/j.bbi.2019.04.001


Blueberries are rich in polyphenols that may be beneficial to cognitive performance and mood. The aim of this systematic review was to evaluate randomized controlled trials investigating the effects of blueberries and blueberry products on measures of cognition and mood. In total, eleven articles (that included 12 studies) were identified using freeze-dried blueberries (n=9 studies), whole blueberries (n=2) and blueberry concentrate (n=1). These studies were conducted in children (n=5), young adults (n=1), and older people with either no known cognitive impairment (n=4) or indicated cognitive impairment (n=2). Eight studies reported blueberry consumption or supplementation at various doses and time lengths to improve measures of cognitive performance, particularly short- and long-term memory and spatial memory. For mood, one study reported significant between-group improvements in positive affect from blueberry products, whereas four studies reported no improvement. Low risk of bias were observed across all studies. Based on the current evidence, blueberries may improve some measures of cognitive performance when consumed for up to six months in duration. However, considerable differences in study design, dosages, and anthocyanin content hinder between-study comparison. The use of standardized blueberry interventions, consideration of placebo formulations, and consistently reported cognitive performance tools are recommended in future trials.

Item Details

Item Type:Refereed Article
Keywords:blueberry, anthocyanins, flavonoid, polyphenol, cognition, mood, nutraceuticals, intervention, human
Research Division:Biomedical and Clinical Sciences
Research Group:Nutrition and dietetics
Research Field:Nutrition and dietetics not elsewhere classified
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Kent, K (Dr Katherine Kent)
ID Code:132077
Year Published:2019
Web of Science® Times Cited:37
Deposited By:UTAS Centre for Rural Health
Deposited On:2019-04-17
Last Modified:2022-08-29

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