University of Tasmania
Browse

File(s) not publicly available

Candidate taste receptors in Drosophila

journal contribution
posted on 2023-05-20, 02:51 authored by Clyne, PJ, Coral WarrCoral Warr, Carlson, JR
Little is known about the molecular mechanisms of taste perception in animals, particularly the initial events of taste signaling. A large and diverse family of seven transmembrane domain proteins was identified from the Drosophila genome database with a computer algorithm that identifies proteins on the basis of structure. Eighteen of 19 genes examined were expressed in the Drosophila labellum, a gustatory organ of the proboscis. Expression was not detected in a variety of other tissues. The genes were not expressed in the labellum of a Drosophila mutant, pox-neuro 70, in which taste neurons are eliminated. Tissue specificity of expression of these genes, along with their structural similarity, supports the possibility that the family encodes a large and divergent family of taste receptors.

History

Publication title

Science

Volume

287

Issue

5459

Pagination

1830-1834

ISSN

0036-8075

Department/School

Tasmanian School of Medicine

Publisher

Amer Assoc Advancement Science

Place of publication

1200 New York Ave, Nw, Washington, USA, Dc, 20005

Repository Status

  • Restricted

Socio-economic Objectives

Expanding knowledge in the biological sciences