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Resveratrol-potential antibacterial agent against foodborne pathogens

Citation

Ma, DSL and Tan, LT and Chan, KG and Yap, WH and Pusparajah, P and Chuah, LH and Ming, LC and Khan, TM and Lee, LH and Goh, BH, Resveratrol-potential antibacterial agent against foodborne pathogens, Frontiers in Pharmacology, 9 pp. 1-16. ISSN 1663-9812 (2018) [Refereed Article]


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Copyright Statement

Copyright 2018 Ma, Tan, Chan, Yap, Pusparajah, Chuah, Ming, Khan, Lee and Goh. Licensed under Creative Commons Attribution 4.0 International (CC BY 4.0) https://creativecommons.org/licenses/by/4.0/

DOI: doi:10.3389/fphar.2018.00102

Abstract

Bacterial foodborne pathogens are a significant health burden and the recent emergence of pathogenic resistant strains due to the excessive use of antibiotics makes it more difficult to effectively treat infections as a result of contaminated food. Awareness of this impending health crisis has spurred the search for alternative antimicrobials with natural plant antimicrobials being among the more promising candidates as these substances have good acceptability and likely low toxicity levels as they have long been used in traditional medicines. Resveratrol (3,5,4'-trihydroxystilbene) is a naturally occurring stilbenoid which has been gaining considerable attention in medical field due to its diverse biological activities - it has been reported to exhibit antioxidant, cardioprotective, anti-diabetic, anticancer, and antiaging properties. Given that resveratrol is phytoalexin, with increased synthesis in response to infection by phytopathogens, there has been interest in exploring its antimicrobial activity. This review aims to provide an overview of the published data on the antibacterial activity of resveratrol against foodborne pathogens, its mechanisms of action as well as its possible applications in food packing and processing; in addition we also summarize the current data on its potential synergism with known antibacterials and future research and applications.

Item Details

Item Type:Refereed Article
Keywords:antibacterial, antibiofilm, foodborne, pathogens, resveratrol
Research Division:Medical and Health Sciences
Research Group:Pharmacology and Pharmaceutical Sciences
Research Field:Clinical Pharmacology and Therapeutics
Objective Division:Expanding Knowledge
Objective Group:Expanding Knowledge
Objective Field:Expanding Knowledge in the Medical and Health Sciences
UTAS Author:Ming, LC (Dr Long Ming)
ID Code:131696
Year Published:2018
Web of Science® Times Cited:15
Deposited By:Pharmacy
Deposited On:2019-04-01
Last Modified:2019-05-03
Downloads:7 View Download Statistics

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