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Microarrays and stage conversion in Toxoplasma gondii

Citation

Ellis, J and Sinclair, D and Morrison, D, Microarrays and stage conversion in Toxoplasma gondii, Trends in Parasitology, 20, (6) pp. 288-295. ISSN 1471-4922 (2004) [Refereed Article]

Copyright Statement

Copyright 2004 Elsevier Ltd.

DOI: doi:10.1016/j.pt.2004.04.006

Abstract

Microarray technology is emerging as a powerful method for the study of those changes in gene expression that occur when a parasite converts from one life cycle stage to another. The use of appropriate experimental design and data analysis methodologies is essential if this technology is to be correctly exploited. In this review, the study of stage conversion in the transformation of Toxoplasma gondii tachyzoites into bradyzoites is considered as an example of where the application of microarrays is revealing exciting new knowledge on underlying molecular mechanisms. The more general application of microarrays in parasitology is also discussed.

Item Details

Item Type:Refereed Article
Keywords:toxoplasmosis, stage conversion
Research Division:Medical and Health Sciences
Research Group:Neurosciences
Research Field:Cellular Nervous System
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Infectious Diseases
UTAS Author:Sinclair, D (Dr Duncan Sinclair)
ID Code:130642
Year Published:2004
Web of Science® Times Cited:5
Deposited By:Wicking Dementia Research and Education Centre
Deposited On:2019-02-06
Last Modified:2019-05-01
Downloads:0

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