Leong, TI and Weiland, TJ and Jelinek, GA and Simpson, S and Brown, CR and Neate, SL and Taylor, KL and O'Kearney, E and Milanzi, E and De Livera, AM, Longitudinal associations of the healthy lifestyle index score with quality of life in people with multiple sclerosis: A prospective cohort study, Frontiers in Neurology, 9 Article 874. ISSN 1664-2295 (2018) [Refereed Article]
Copyright 2018 Leong, Weiland, Jelinek, Simpson, Brown, Neate, Taylor, O'Kearney, Milanzi and De Livera. Licensed under Creative Commons Attribution 4.0 International (CC BY 4.0) https://creativecommons.org/licenses/by/4.0/
Methods: People with MS were recruited to participate in a comprehensive online survey regarding their demographic and clinical characteristics, health-related quality of life (HRQOL), and lifestyle behaviors including physical activity, alcohol consumption, cigarette smoking, body mass index, and dietary habits measured at baseline and 2.5-year follow-up. A combined healthy lifestyle index score (HLIS) was constructed by assigning scores of 0-4 to each of the lifestyle risk factors, for which higher values indicate healthier lifestyle behavior. Multivariable linear regression modeling was used to assess whether the HLIS at baseline was associated with the physical and mental HRQOL over the study period in this sample of people with MS.
Results: Of 2,466 participants with confirmed MS, 1,401 (57%) completed the follow-up. Multivariable linear regression analyses demonstrated that every 5-point increase (of a possible total of 20) in the baseline HLIS was associated with 1.7 (95% CI: 0.2-3.2) and 2.5 (95% CI: 1.0-4.0) higher scores in the change in physical and mental HRQOL components from baseline to follow-up respectively.
Conclusion: Findings suggest the importance of healthy lifestyle behavior in quality of life in MS. A healthy lifestyle program focusing on these behaviors has the potential to positively influence health-related quality of life for people with MS.
|Item Type:||Refereed Article|
|Keywords:||QOL, health outcomes, lifestyle, multiple sclerosis, quality of life, risk factors|
|Research Division:||Medical and Health Sciences|
|Research Group:||Public Health and Health Services|
|Objective Group:||Clinical Health (Organs, Diseases and Abnormal Conditions)|
|Objective Field:||Nervous System and Disorders|
|UTAS Author:||Simpson, S (Dr Steve Simpson JR)|
|Web of Science® Times Cited:||1|
|Deposited By:||Menzies Institute for Medical Research|
|Downloads:||62 View Download Statistics|
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