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Role of lactic acid probiotic bacteria in IBD


Vemuri, R and Gundamaraju, R and Eri, R, Role of lactic acid probiotic bacteria in IBD, Current Pharmaceutical Design, 23, (16) pp. 2352-2355. ISSN 1381-6128 (2017) [Review Several Works]

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2017 Bentham Science Publishers

DOI: doi:10.2174/1381612823666170207100025


Background: IBD is considered as one of the major public health concerns worldwide. The pathophysiology and gut microbial alteration during inflammatory bowel disease (IBD) are still not completely understood. Gut microbiota is implicated in most of the gastro-intestinal (GI) diseases including IBD. From the time of gut microbiota establishment and through aging, it undergoes a lot of changes in the composition.

Methods: In a healthy state, the composition of beneficial microbes in the gut is comparatively higher and due to factors such as malnutrition, use of antibiotics and any underlying diseases allow the colonization and invasion of pathogens.

Results: A careful manipulation of gut microbiota during disease conditions such as IBD is required. Probiotics are natural, safe and useful interventions for GI diseases.

Conclusion: Lactic acid probiotic bacteria have shown many beneficial effects in various gastrointestinal and inflammatory disorders. This review focuses on the use of probiotics in IBD and possible mechanism of probiotics in inflammation conditions.

Item Details

Item Type:Review Several Works
Keywords:probiotics, IBD, gut microbiota
Research Division:Biological Sciences
Research Group:Microbiology
Research Field:Infectious agents
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Vemuri, R (Mr Ravichandra Vemuri)
UTAS Author:Gundamaraju, R (Mr Rohit Gundamaraju)
UTAS Author:Eri, R (Associate Professor Raj Eri)
ID Code:129777
Year Published:2017
Web of Science® Times Cited:14
Deposited By:Health Sciences
Deposited On:2018-12-18
Last Modified:2018-12-18

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