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Autoradiographic localisation of substance P (NK1) receptors in human primary visual cortex

Citation

Kus, L and Mazzone, SB and Paxinos, G and Geraghty, DP, Autoradiographic localisation of substance P (NK1) receptors in human primary visual cortex, Brain Research, 794, (2) pp. 309-312. ISSN 0006-8993 (1998) [Refereed Article]

DOI: doi:10.1016/S0006-8993(98)00270-4

Abstract

This study utilised autoradiography to examine [125I]-Bolton Hunter substance P (BHSP) binding in postmortem human visual cortex. In the primary visual area, layers I-III, IVC and VI exhibited low levels of BHSP binding, while high levels were observed in layers IVB and V. Because cells in layers IVB and V are known to be involved in processing direction-specific stimuli, it is possible that SP plays a role in modulating this visual process.

Item Details

Item Type:Refereed Article
Research Division:Medical and Health Sciences
Research Group:Pharmacology and Pharmaceutical Sciences
Research Field:Basic Pharmacology
Objective Division:Health
Objective Group:Other Health
Objective Field:Health not elsewhere classified
Author:Mazzone, SB (Mr Stuart Brett Mazzone)
Author:Geraghty, DP (Professor Dominic Geraghty)
ID Code:12925
Year Published:1998
Web of Science® Times Cited:7
Deposited By:Health Sciences A
Deposited On:1998-08-01
Last Modified:2011-08-05
Downloads:0

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