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Autoradiographic localisation of substance P (NK1) receptors in human primary visual cortex

journal contribution
posted on 2023-05-16, 11:02 authored by Kus, L, Mazzone, SB, Paxinos, G, Dominic GeraghtyDominic Geraghty
This study utilised autoradiography to examine [125I]-Bolton Hunter substance P (BHSP) binding in postmortem human visual cortex. In the primary visual area, layers I-III, IVC and VI exhibited low levels of BHSP binding, while high levels were observed in layers IVB and V. Because cells in layers IVB and V are known to be involved in processing direction-specific stimuli, it is possible that SP plays a role in modulating this visual process.

History

Publication title

Brain Research

Volume

794

Pagination

309-312

ISSN

0006-8993

Department/School

School of Health Sciences

Publisher

Elsevier

Place of publication

The Netherlands

Repository Status

  • Restricted

Socio-economic Objectives

Other health not elsewhere classified

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