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Capstone laboratory experiment investigating key features of palladium-catalyzed Suzuki-Miyaura cross-coupling reactions
Citation
Pullen, R and Olding, A and SMith, JA and Bissember, AC, Capstone laboratory experiment investigating key features of palladium-catalyzed Suzuki-Miyaura cross-coupling reactions, Journal of Chemical Education pp. 1-5. ISSN 0021-9584 (2018) [Refereed Article]
Copyright Statement
Copyright 2018 American Chemical Society and Division of Chemical Education, Inc.
DOI: doi:10.1021/acs.jchemed.7b00964
Abstract
This two-part laboratory experiment is concerned with investigating key aspects of the Suzuki-Miyaura cross-coupling reaction. The first part of this experiment utilizes high-throughput experimentation techniques to reinforce, explore, and extend fundamental concepts that are presented in the classroom. In contrast, the second part employs guided-inquiry learning strategies to challenge students to design, set up, and perform a preparative-scale Suzuki-Miyaura reaction and suggest workup and isolation protocols. By design, this experiment, which represents one of the final experiments performed in the third-year undergraduate chemistry laboratory program, serves as a capstone learning experience for students.
Item Details
Item Type: | Refereed Article |
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Keywords: | laboratory instruction. inquiry-based/discovery learning, catalysis |
Research Division: | Chemical Sciences |
Research Group: | Organic chemistry |
Research Field: | Organic chemical synthesis |
Objective Division: | Expanding Knowledge |
Objective Group: | Expanding knowledge |
Objective Field: | Expanding knowledge in the chemical sciences |
UTAS Author: | Pullen, R (Mr Reyne Pullen) |
UTAS Author: | Olding, A (Mr Angus Olding) |
UTAS Author: | SMith, JA (Professor Jason Smith) |
UTAS Author: | Bissember, AC (Associate Professor Alex Bissember) |
ID Code: | 128881 |
Year Published: | 2018 |
Web of Science® Times Cited: | 9 |
Deposited By: | Chemistry |
Deposited On: | 2018-10-20 |
Last Modified: | 2022-08-19 |
Downloads: | 0 |
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