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Capstone laboratory experiment investigating key features of palladium-catalyzed Suzuki-Miyaura cross-coupling reactions
journal contribution
posted on 2023-05-19, 22:02 authored by Pullen, R, Angus OldingAngus Olding, Jason SmithJason Smith, Alexander BissemberAlexander BissemberThis two-part laboratory experiment is concerned with investigating key aspects of the Suzuki-Miyaura cross-coupling reaction. The first part of this experiment utilizes high-throughput experimentation techniques to reinforce, explore, and extend fundamental concepts that are presented in the classroom. In contrast, the second part employs guided-inquiry learning strategies to challenge students to design, set up, and perform a preparative-scale Suzuki-Miyaura reaction and suggest workup and isolation protocols. By design, this experiment, which represents one of the final experiments performed in the third-year undergraduate chemistry laboratory program, serves as a capstone learning experience for students.
History
Publication title
Journal of Chemical EducationPagination
1-5ISSN
0021-9584Department/School
College Office - College of Sciences and EngineeringPublisher
Amer Chemical SocPlace of publication
1155 16Th St, Nw, Washington, USA, Dc, 20036Rights statement
Copyright 2018 American Chemical Society and Division of Chemical Education, Inc.Repository Status
- Restricted