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Association of childhood obesity with female infertility in adulthood: a 25-year follow-up study
Citation
He, Y and Tian, J and Oddy, WH and Dwyer, T and Venn, AJ, Association of childhood obesity with female infertility in adulthood: a 25-year follow-up study, Fertility and Sterility, 110, (4) pp. 596-604.e1. ISSN 0015-0282 (2018) [Refereed Article]
Copyright Statement
Copyright 2018 American Society for Reproductive Medicine
DOI: doi:10.1016/j.fertnstert.2018.05.011
Abstract
Design: Prospective longitudinal study.
Setting: Not applicable.
Intervention(s): None.
Patient(s): A total of 1,544 girls, aged 7-15 years in 1985, and who completed questionnaires at follow-up in 2004-2006 and/or 2009-2011.
Main outcome measure(s): Infertility was defined as having difficulty conceiving (had tried for ≥12 months to become pregnant without succeeding) or having seen a doctor because of trouble becoming pregnant.
Result(s): At ages from 7-11 years, girls at both the lower and upper end of the body mass index (BMI) z score had increased risk of infertility. Compared with normal weight girls, those with obesity at ages 7-11 years were more likely in adulthood to report infertility (adjusted relative risk [aRR] = 2.94, 95% confidence interval [CI] 1.48-5.84), difficulty conceiving (aRR = 3.89, 95% CI 1.95-7.77), or having seen a doctor because of trouble becoming pregnant (aRR = 3.65, 95% CI 1.90-7.02) after adjusting for childhood age, follow-up length, highest parental education, and marital status.
Conclusion(s): Childhood obesity before 12 years of age appears to increase the risk of female infertility in later life.
Item Details
Item Type: | Refereed Article |
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Keywords: | childhood, body composition, body mass index, infertility, waist-to-height ratio |
Research Division: | Health Sciences |
Research Group: | Epidemiology |
Research Field: | Epidemiology not elsewhere classified |
Objective Division: | Health |
Objective Group: | Public health (excl. specific population health) |
Objective Field: | Preventive medicine |
UTAS Author: | He, Y (Ms Ye He) |
UTAS Author: | Tian, J (Dr Jing Tian) |
UTAS Author: | Oddy, WH (Professor Wendy Oddy) |
UTAS Author: | Dwyer, T (Professor Terry Dwyer) |
UTAS Author: | Venn, AJ (Professor Alison Venn) |
ID Code: | 128846 |
Year Published: | 2018 |
Web of Science® Times Cited: | 6 |
Deposited By: | Menzies Institute for Medical Research |
Deposited On: | 2018-10-17 |
Last Modified: | 2018-12-12 |
Downloads: | 0 |
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