Bhatia, R and Yeoh, SW and Vaz, K and Studd, C and Wilson, J and Bell, S and Otahal, P and Venn, A, Inflammatory bowel disease incidence, prevalence and twelve-month initial disease course in Tasmania, Australia, Internal Medicine Journal pp. 1-30. ISSN 1444-0903 (2018) [Refereed Article]
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Aims: This study estimates the one-year incidence and point prevalence of IBD in the state of Tasmania, Australia. It also reports clinical outcomes after twelve months of diagnosis in an incident cohort.
Methods: A prospective, population-based study was performed collecting prevalent and incident state-wide cases from 1st June 2013 to 31st May 2014. Case data were identified from specialist doctors, pathology databases and hospital records. Age-standardised rates (ASRs) were calculated based on World Health Organization 2000 standard population characteristics. Incident cases were followed up twelve months after diagnosis.
Results: There were 1719 prevalent cases: ASRs for IBD, Crohn's disease (CD), ulcerative colitis (UC) and inflammatory bowel disease unclassified (IBDU) prevalence were 303.9, 165.5, 131.4 and 6.9 per 100,000 respectively. Prevalent CD cases were younger, with greater immunomodulator/biologic use and bowel resections. There were 149 incident cases: ASRs for IBD, CD, UC and IBDU incidence were 29.5, 15.4, 12.4, and 1.7 per 100,000 respectively. Incident CD cases were more likely than UC or IBDU to require escalation of medical therapy, hospitalisation, and bowel resection especially among those with penetrating or stricturing disease. They had longer duration of symptoms prior to diagnosis.
Conclusions: IBD prevalence and incidence rates are high in Tasmania, comparable to data from other Australasian studies and those from Northern Europe and America. Poorer twelve month clinical outcomes occurred in complicated CD, with greater use of healthcare resources.
|Item Type:||Refereed Article|
|Keywords:||Crohn’s disease, epidemiology, hospitalization, treatment outcome, ulcerative colitis|
|Research Division:||Health Sciences|
|Research Field:||Epidemiology not elsewhere classified|
|Objective Group:||Public health (excl. specific population health)|
|Objective Field:||Preventive medicine|
|UTAS Author:||Bhatia, R (Dr Rajesh Bhatia)|
|UTAS Author:||Otahal, P (Mr Petr Otahal)|
|UTAS Author:||Venn, A (Professor Alison Venn)|
|Web of Science® Times Cited:||2|
|Deposited By:||Menzies Institute for Medical Research|
|Downloads:||37 View Download Statistics|
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