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Hypothalamic demyelination causing panhypopituitarism


Dixon-Douglas, J and Burgess, J and Dreyer, M, Hypothalamic demyelination causing panhypopituitarism, Internal Medicine Journal, 48, (5) pp. 580-582. ISSN 1444-0903 (2018) [Contribution to Refereed Journal]

Copyright Statement

2018 Royal Australasian College of Physicians

DOI: doi:10.1111/imj.13787


Hypothalamic involvement in multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) is rare and endocrinopathies involving the hypothalamic-pituitary axis in patients with demyelinating conditions have rarely been reported. We present two cases of MS/NMOSD with associated hypothalamic-pituitary involvement and subsequent hypopituitarism, including the first report of a patient with hypothalamic demyelination causing panhypopituitarism. Differential diagnoses, including alemtuzumab-related and primary pituitary pathology are discussed.

Item Details

Item Type:Contribution to Refereed Journal
Keywords:demyelinating disease; hypopituitarism; hypothalamus; multiple sclerosis; neuromyelitis optica
Research Division:Biomedical and Clinical Sciences
Research Group:Clinical sciences
Research Field:Endocrinology
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Burgess, J (Professor John Burgess)
ID Code:128405
Year Published:2018
Web of Science® Times Cited:1
Deposited By:Medicine
Deposited On:2018-09-19
Last Modified:2019-01-09

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