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Data on prolonged morphine-induced antinociception and behavioral inhibition in older rats
Citation
Paul, AK and Gueven, N and Dietis, N, Data on prolonged morphine-induced antinociception and behavioral inhibition in older rats, Data in Brief, 19 pp. 183-188. ISSN 2352-3409 (2018) [Refereed Article]
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Copyright Statement
Copyright 2018 the authors. Licensed under Creative Commons Attribution 4.0 International (CC BY 4.0) https://creativecommons.org/licenses/by/4.0/
DOI: doi:10.1016/j.dib.2018.05.001
Abstract
This article contains supportive data related to a research article entitled "Age-dependent antinociception and behavioral inhibition by morphine" (Paul et al., 2018) [1]. Antinociceptive latencies of 8 and 24-week old rats were obtained from tail-flick and hot plate assays after morphine treatment. Motor behavioral effects were measured at different time-points using automated infrared tracking in an open-field arena. Residual morphine content in post-mortem tissues were measured 240 min post-treatment. Concurrent measurements of antinociception, motor behavior and residual morphine content in post-mortem tissues of 8-week and 24-week old morphine-treated rats provide an integrated assessment of age-related differences.
Item Details
| Item Type: | Refereed Article |
|---|---|
| Keywords: | morphine |
| Research Division: | Medical and Health Sciences |
| Research Group: | Pharmacology and Pharmaceutical Sciences |
| Research Field: | Basic Pharmacology |
| Objective Division: | Expanding Knowledge |
| Objective Group: | Expanding Knowledge |
| Objective Field: | Expanding Knowledge in the Medical and Health Sciences |
| Author: | Paul, AK (Mr Alok Paul) |
| Author: | Gueven, N (Dr Nuri Guven) |
| Author: | Dietis, N (Dr Nikolas Dietis) |
| ID Code: | 127883 |
| Year Published: | 2018 |
| Deposited By: | Pharmacy |
| Deposited On: | 2018-08-20 |
| Last Modified: | 2018-09-10 |
| Downloads: | 8 View Download Statistics |
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