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Data on prolonged morphine-induced antinociception and behavioral inhibition in older rats

Citation

Paul, AK and Gueven, N and Dietis, N, Data on prolonged morphine-induced antinociception and behavioral inhibition in older rats, Data in Brief, 19 pp. 183-188. ISSN 2352-3409 (2018) [Refereed Article]


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Copyright Statement

Copyright 2018 the authors. Licensed under Creative Commons Attribution 4.0 International (CC BY 4.0) https://creativecommons.org/licenses/by/4.0/

DOI: doi:10.1016/j.dib.2018.05.001

Abstract

This article contains supportive data related to a research article entitled "Age-dependent antinociception and behavioral inhibition by morphine" (Paul et al., 2018) [1]. Antinociceptive latencies of 8 and 24-week old rats were obtained from tail-flick and hot plate assays after morphine treatment. Motor behavioral effects were measured at different time-points using automated infrared tracking in an open-field arena. Residual morphine content in post-mortem tissues were measured 240 min post-treatment. Concurrent measurements of antinociception, motor behavior and residual morphine content in post-mortem tissues of 8-week and 24-week old morphine-treated rats provide an integrated assessment of age-related differences.

Item Details

Item Type:Refereed Article
Keywords:morphine
Research Division:Medical and Health Sciences
Research Group:Pharmacology and Pharmaceutical Sciences
Research Field:Basic Pharmacology
Objective Division:Expanding Knowledge
Objective Group:Expanding Knowledge
Objective Field:Expanding Knowledge in the Medical and Health Sciences
Author:Paul, AK (Mr Alok Paul)
Author:Gueven, N (Dr Nuri Guven)
Author:Dietis, N (Dr Nikolas Dietis)
ID Code:127883
Year Published:2018
Deposited By:Pharmacy
Deposited On:2018-08-20
Last Modified:2018-09-10
Downloads:8 View Download Statistics

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