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Data on prolonged morphine-induced antinociception and behavioral inhibition in older rats


Paul, A and Gueven, N and Dietis, N, Data on prolonged morphine-induced antinociception and behavioral inhibition in older rats, Data in Brief, 19 pp. 183-188. ISSN 2352-3409 (2018) [Contribution to Refereed Journal]


Copyright Statement

Copyright 2018 the authors. Licensed under Creative Commons Attribution 4.0 International (CC BY 4.0)

DOI: doi:10.1016/j.dib.2018.05.001


This article contains supportive data related to a research article entitled "Age-dependent antinociception and behavioral inhibition by morphine" (Paul et al., 2018) [1]. Antinociceptive latencies of 8 and 24-week old rats were obtained from tail-flick and hot plate assays after morphine treatment. Motor behavioral effects were measured at different time-points using automated infrared tracking in an open-field arena. Residual morphine content in post-mortem tissues were measured 240 min post-treatment. Concurrent measurements of antinociception, motor behavior and residual morphine content in post-mortem tissues of 8-week and 24-week old morphine-treated rats provide an integrated assessment of age-related differences.

Item Details

Item Type:Contribution to Refereed Journal
Keywords:physical activity, proteomics, metabolism, beta-agonists, adrenoceptors, adrenergic, VO2max, terbutaline, HIT, athletes
Research Division:Biomedical and Clinical Sciences
Research Group:Pharmacology and pharmaceutical sciences
Research Field:Basic pharmacology
Objective Division:Expanding Knowledge
Objective Group:Expanding knowledge
Objective Field:Expanding knowledge in the health sciences
UTAS Author:Paul, A (Dr Alok Paul)
UTAS Author:Gueven, N (Dr Nuri Guven)
UTAS Author:Dietis, N (Dr Nikolas Dietis)
ID Code:127883
Year Published:2018
Web of Science® Times Cited:4
Deposited By:Pharmacy
Deposited On:2018-08-20
Last Modified:2020-03-17
Downloads:104 View Download Statistics

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