Maya, F and Estela, JM and Cerda, V, Interfacing on-line solid phase extraction with monolithic column multisyringe chromatography and chemiluminescence detection: an effective tool for fast, sensitive and selective determination of thiazide diuretics, Talanta, 80, (3) pp. 1333-1340. ISSN 0039-9140 (2010) [Refereed Article]
Copyright 2009 Elsevier B.V.
For the determination of three thiazide compounds named hydroflumethiazide, furosemide and bendroflumethiazide, the proposed set-up provided with the preconcentration of only 1 mL of sample, limits of detection of 3, 60 and 40 μg L−1, respectively. Furthermore wide linear dynamic ranges of 6–4000, 140–20,000 and 90–40,000 μg L−1, respectively, were obtained. Besides of this, a high injection throughput of 12 h−1 was also achieved. As in sports, thiazide diuretics are prohibited substances, the proposed method has been applied to their determination in urine samples. Furthermore the potential of the proposed method as a fast-screening approach for emerging contaminants in waters has been also tested by applying it to well water and leachates from a solid waste landfill.
|Item Type:||Refereed Article|
|Keywords:||flow analysis, solid phase extraction, monolithic column, multisyringe chromatography, chemiluminescence, thiazide diuretics|
|Research Division:||Chemical Sciences|
|Research Group:||Analytical chemistry|
|Research Field:||Flow analysis|
|Objective Division:||Expanding Knowledge|
|Objective Group:||Expanding knowledge|
|Objective Field:||Expanding knowledge in the chemical sciences|
|UTAS Author:||Maya, F (Mr Fernando Maya Alejandro)|
|Web of Science® Times Cited:||49|
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