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A systematic literature review of the effect of anthocyanins on gut microbiota populations

Citation

Igwe, EO and Charlton, KE and Probst, YC and Kent, K and Netzel, ME, A systematic literature review of the effect of anthocyanins on gut microbiota populations, Journal of Human Nutrition and Dietetics ISSN 0952-3871 (2018) [Refereed Article]

Copyright Statement

Copyright 2018 The British Dietetic Association Ltd.

DOI: doi:10.1111/jhn.12582

Abstract

Background: Evidence has shown that anthocyanins, a subclass of polyphenol, are metabolised in the gut, modulate bacterial species and exert bioactive effects through this interaction.

Methods: A systematic literature review was undertaken to determine the level of current evidence for the association between anthocyanin intake and changes in gut microbiota populations. The studies included were also assessed for the different techniques used in microbiota determination. Following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, scientific databases, including Scopus, PubMed, ScienceDirect, Web of Science and MEDLINE, were searched up to June 2017. Details on population/sample, study design, intervention/control, dosage and method of microbiota determination were extracted.

Results: Six studies (three in vitro, two animal and one human trials) were included in the review, which showed that anthocyanins induced a significant proliferative effect on Bifidobacterium spp., known for their wide use in probiotics and for the treatment of irritable bowel syndrome. There was also an observed inhibition of Clostridium histolyticum, which was shown to be pathogenic in humans. The depth of analysis is an important consideration for the choice of microbiota determination technique with respect to a comprehensive, high-resolution microbiota analysis or analysis of the main microbiota taxa.

Conclusions: Very limited research has been carried out in the area of anthocyanins and gut microbiota; beneficial effects have generally been observed, and further clinical trials in humans are needed to confirm changes to gut microbes in relation to dietary anthocyanin intake and potential health benefits.

Item Details

Item Type:Refereed Article
Keywords:systematic literature review, anthocyanins, gut microbiota
Research Division:Medical and Health Sciences
Research Group:Nutrition and Dietetics
Research Field:Nutrition and Dietetics not elsewhere classified
Objective Division:Health
Objective Group:Public Health (excl. Specific Population Health)
Objective Field:Nutrition
Author:Kent, K (Dr Katherine Kent)
ID Code:127096
Year Published:2018
Deposited By:Centre for Rural Health
Deposited On:2018-07-10
Last Modified:2018-09-20
Downloads:0

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