An investigation of the previously unexamined ancient Tasmanian clone Lomatia tasmanica W. M. Curtis (Proteaceae) and two other endemic species Lomatia tinctoria R. Br. and Lomatia polymorpha (Labill.) R. Br. was undertaken. This represents the first extensive natural products study in which individual phytochemical components have been isolated and identified from these three Lomatia species. Extraction of L. tasmanica leaves provided the naphthoquinone juglone (0.34% w/w), and n-alkanes nonacosane and heptacosane (0.30% w/w combined). L. polymorpha afforded the flavonoid glycosides dihydroquercetin 3-O-β-D-xyloside (0.22% w/w) and quercetin 3-O-β-_D-glucose (0.14% w/w), as well as the naphthalene glucoside 1,4,8-trihydroxynaphthalene-1-O-β-_D-glucose (0.04% w/w) and 4-O-p-coumaroyl-_D-glucose (0.03% w/w). In addition, both L. polymorpha and L. tinctoria contained juglone (0.32% w/w and 0.58% w/w, respectively). L. polymorpha provided tetracosan-1-ol, hexacosan-1-ol and octacosan-1-ol (0.07% w/w combined), while L. tinctoria gave nonacosane (0.13% w/w). Analysis of three individual specimens from each of the three species demonstrated consistency in the respective phytochemical profiles of these populations and tentatively suggests limited intraspecific variation.

Item Type:	Refereed Article
Keywords:	Lomatia tasmanica, Lomatia polymorpha, Lomatia tinctoria, Proteaceae, naphthoquinones, flavonoid glycosides, n-alkanes, n-alcohols, pressurized hot water extraction
Research Division:	Chemical Sciences
Research Group:	Organic Chemistry
Research Field:	Natural Products Chemistry
Objective Division:	Expanding Knowledge
Objective Group:	Expanding Knowledge
Objective Field:	Expanding Knowledge in the Chemical Sciences
Author:	Deans, BJ (Miss Bianca Deans)
Author:	Tedone, L (Ms Laura Tedone)
Author:	Bissember, AC (Dr Alex Bissember)
Author:	Smith, JA (Associate Professor Jason Smith)
ID Code:	126401
Year Published:	2018
Deposited By:	Chemistry
Deposited On:	2018-06-08
Last Modified:	2018-07-27
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