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The cascading pathogenic consequences of Sarcoptes scabiei infection that manifest in host disease

Citation

Martin, AM and Fraser, TA and Lesku, JA and Simpson, K and Roberts, GL and Garvey, J and Polkinghorne, A and Burridge, CP and Carver, S, The cascading pathogenic consequences of Sarcoptes scabiei infection that manifest in host disease, Royal Society Open Science, 5, (4) Article 180018. ISSN 2054-5703 (2018) [Refereed Article]


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Copyright Statement

2018 The Authors. Licensed under Creative Commons Attribution 4.0 International (CC BY 4.0) https://creativecommons.org/licenses/by/4.0/

DOI: doi:10.1098/rsos.180018

Abstract

Sarcoptic mange, caused by the parasitic mite Sarcoptes scabiei, causes a substantive burden of disease to humans, domestic animals and wildlife, globally. There are many effects of S. scabiei infection, culminating in the disease which hosts suffer. However, major knowledge gaps remain on the pathogenic impacts of this infection. Here, we focus on the bare-nosed wombat host (Vombatus ursinus) to investigate the effects of mange on: (i) host heat loss and thermoregulation, (ii) field metabolic rates, (iii) foraging and resting behaviour across full circadian cycles, and (iv) fatty acid composition in host adipose, bone marrow, brain and muscle tissues. Our findings indicate that mange-infected V. ursinus lose more heat to the environment from alopeciaaffected body regions than healthy individuals. Additionally, mange-infected individuals have higher metabolic rates in the wild. However, these metabolic demands are difficult to meet, because infected individuals spend less time foraging and more time inactive relative to their healthy counterparts, despite being outside of the burrow for longer.

Item Details

Item Type:Refereed Article
Keywords:mange, disease, physiology, Vombatus ursinus, sarcoptic mange, pathophysiology, metabolic rate, fatty acid composition, time budget
Research Division:Environmental Sciences
Research Group:Environmental Science and Management
Research Field:Conservation and Biodiversity
Objective Division:Expanding Knowledge
Objective Group:Expanding Knowledge
Objective Field:Expanding Knowledge in the Environmental Sciences
UTAS Author:Martin, AM (Ms Alynn Martin)
UTAS Author:Fraser, TA (Ms Tamieka Fraser)
UTAS Author:Burridge, CP (Associate Professor Christopher Burridge)
UTAS Author:Carver, S (Dr Scott Carver)
ID Code:126273
Year Published:2018
Web of Science® Times Cited:5
Deposited By:Zoology
Deposited On:2018-06-01
Last Modified:2019-03-05
Downloads:45 View Download Statistics

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