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Advanced Stationary Phases for HPLC

Citation

Nesterenko, PN and Kazakevich, YV, Advanced Stationary Phases for HPLC, Current Chromatography, 5, (1) pp. 3-4. ISSN 2213-2414 (2018) [Non Refereed Article]


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Abstract

The preparation and characterisation of new stationary phases remain one of the most challenging and intensively developing research areas in chromatographic sciences. There are two main areas in adsorbent development: surface chemistry and adsorbent geometry. Chemical properties of adsorbent surface are the main factors that define chromatographic selectivity and adsorbent geometry (particle size and porosity type) which are also the key elements that define column efficiency. These combined factors determine overall chromatographic performance. Additionally, for some particular modes of liquid chromatography, the significant improvement of auxiliary physico-chemical properties of stationary phases is often required. This includes an elevated mechanical stability in ultra-high pressure liquid chromatography, a high thermal stability in high temperature liquid chromatography, a superior biocompatibility in biochromatography, a broader pH range of hydrolytic stability for the separation of various inorganic species and many other properties and others. Unsurprisingly, the development of advanced stationary phases for liquid chromatography was selected as a theme for the first Special Issue of the journal Current Chromatography.

Item Details

Item Type:Non Refereed Article
Keywords:adsorbent geometry, biochromatography, HPLC, stationary phases, silica hydride, surface chemistry
Research Division:Chemical Sciences
Research Group:Analytical Chemistry
Research Field:Separation Science
Objective Division:Expanding Knowledge
Objective Group:Expanding Knowledge
Objective Field:Expanding Knowledge in the Chemical Sciences
UTAS Author:Nesterenko, PN (Professor Pavel Nesterenko)
ID Code:126239
Year Published:2018
Deposited By:Chemistry
Deposited On:2018-05-30
Last Modified:2018-06-04
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