eCite Digital Repository

Haematopoietic stem cell transplantation for severe combined immunodeficiency: Long-term health outcomes and patient perspectives

Citation

Lee, AYS and Frith, K and Schneider, L and Ziegler, JB, Haematopoietic stem cell transplantation for severe combined immunodeficiency: Long-term health outcomes and patient perspectives, Journal of Paediatrics and Child Health, 53, (8) pp. 766-770. ISSN 1034-4810 (2017) [Refereed Article]

Copyright Statement

Copyright 2017 Paediatrics and Child Health Division (The Royal Australasian College of Physicians)

DOI: doi:10.1111/jpc.13560

Abstract

Aim: To examine the long-term follow-up and health outcomes of patients who have undergone haematopoietic stem cell transplant (HSCT) forsevere combined immunodeficiency (SCID).

Methods: Through a structured questionnaire, we examined follow-up arrangements and long-term health outcomes in 22 children who havehad a successful HSCT for SCID during the period of 1984–2012 at the Sydney Children’s Hospital, Sydney, Australia.

Results: Most children considered themselves healthy and ‘cured’ from SCID. Whilst many children enjoy relatively good bio-social health out-comes, specific negative health outcomes and absenteeism from school were perceived negatively. Two-thirds of children see their general practi-tioner or specialist regularly; however, there did not appear to be consistency with the nature of this follow-up.

Conclusion: The findings from our study highlight the comple x bio-psychosocial health needs of post-HSC T SCID childr en and encour age SCID centr es toconsider a multidisciplinary approach to their follow -up . Further studies into the determinants of patients’ perceptions of their health are needed.

Item Details

Item Type:Refereed Article
Keywords:haematopoietic stem cell transplant, immunology, outcomes, severe combined immunodeficiency
Research Division:Medical and Health Sciences
Research Group:Immunology
Research Field:Cellular Immunology
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Immune System and Allergy
UTAS Author:Lee, AYS (Dr Adrian Lee)
ID Code:126109
Year Published:2017
Web of Science® Times Cited:2
Deposited By:Medicine
Deposited On:2018-05-23
Last Modified:2018-09-11
Downloads:0

Repository Staff Only: item control page